Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27887822 | 0.99 | SMN1; SMN2 (0.45) | SMN1; SMN2POLBNPSR1TSHRABCG2 | |
| SCHEMBL27904608 | 0.83 | SMN1; SMN2 (0.46) | SMN1; SMN2POLBNPSR1TSHRABCG2 | |
| Hydrochloric Acid SCHEMBL27887778 | 0.82 | SMN1; SMN2 (0.45) | SMN1; SMN2POLBNPSR1TSHRABCG2 | |
| SCHEMBL2154289 | 0.78 | SMN1; SMN2 (0.48) | SMN1; SMN2POLBNPSR1TSHRALDH1A1 | |
| Hydrochloric Acid SCHEMBL27887791 | 0.77 | SMN1; SMN2 (0.47) | SMN1; SMN2POLBNPSR1TSHRALDH1A1 | |
| SCHEMBL16183299 | 0.75 | KCNA5 (0.57) | SMN1; SMN2POLBNPSR1TSHRALDH1A1 | |
| SCHEMBL21348278 | 0.72 | CYP1A2 (0.67) | SMN1; SMN2POLBNPSR1TSHRALDH1A1 | |
| SCHEMBL16183288 | 0.70 | CYP11B1 (0.40) | SMN1; SMN2POLBNPSR1TSHRABCG2 | |
| SCHEMBL20273439 | 0.70 | ABCG2 (0.57) | NPSR1TSHRABCG2ALDH1A1HSD17B10 | |
| SCHEMBL28995118 | 0.70 | CYP3A4 (0.34) | SMN1; SMN2POLBTSHRALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105218516-A | Therapeutic compounds and related methods of use | OTSUKA PHARMA CO LTD | 2016-01-06 | — | — | CN | disclosed |
| CN-102883723-B | Therapeutic compounds and related methods of use | OTSUKA PHARMACEUTICAL CO.,LTD. (JP) | 2015-09-16 | — | — | CN | disclosed |
| CN-102883723-A | Therapeutic compounds and related methods of use | GALENEA CORP | 2013-01-16 | — | — | CN | disclosed |