Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 2/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.52 |
| ▸ | TSHR | P16473 | 5/20 | 0.52 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | CLK1 | P49759 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21348278 | 0.81 | CYP1A2 (0.67) | ALDH1A1CYP1A2CYP3A4TSHRCLK4 | |
| SCHEMBL12170689 | 0.76 | KCNA5 (0.77) | KCNA5KCNH2ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL27904599 | 0.75 | SMN1; SMN2 (0.46) | ALDH1A1CYP1A2CYP3A4TSHRCLK4 | |
| SCHEMBL27904608 | 0.75 | SMN1; SMN2 (0.46) | ALDH1A1CYP1A2CYP3A4TSHRCLK4 | |
| Hydrochloric Acid SCHEMBL27887822 | 0.74 | SMN1; SMN2 (0.45) | ALDH1A1CYP1A2CYP3A4TSHRCLK4 | |
| Hydrochloric Acid SCHEMBL27887778 | 0.74 | SMN1; SMN2 (0.45) | ALDH1A1CYP1A2CYP3A4TSHRCLK4 | |
| SCHEMBL12170690 | 0.74 | PDE5A (0.74) | KCNA5KCNH2ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL16716602 | 0.73 | CYP19A1 (0.50) | KCNA5KCNH2ALDH1A1CYP3A4TSHR | |
| SCHEMBL12169992 | 0.73 | KCNA5 (1.00) | KCNA5KCNH2JAK2LCKLYN | |
| SCHEMBL17829276 | 0.72 | CYP11B1 (0.49) | KCNA5KCNH2ALDH1A1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140315886-A1 | QUINAZOLINES AS THERAPEUTIC COMPOUNDS AND RELATED METHODS OF USE | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2014-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140315886-A1 | QUINAZOLINES AS THERAPEUTIC COMPOUNDS AND RELATED METHODS OF USE | PPP2CA, PPP4C, PPP3CB | KCNA5 4457/4885KCNH2 4620/4885ALDH1A1 1687/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.