Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1B | P47901 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CHUK | O15111 | 3/20 | 0.46 |
| ▸ | INSR | P06213 | 3/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.46 |
| ▸ | CAMKK2 | Q96RR4 | 3/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Morpholine SCHEMBL27904602 | 0.96 | AVPR1B (0.46) | AVPR1BMEN1LMNACYP1A2CYP3A4 | |
| SCHEMBL27887782 | 0.86 | GBA1 (0.43) | KMT2APOLBRAB9A | |
| SCHEMBL2154997 | 0.86 | CYP1A2 (0.51) | AVPR1BMEN1LMNACYP1A2CYP3A4 | |
| SCHEMBL14474922 | 0.82 | AVPR1B (0.54) | AVPR1BMEN1LMNACYP1A2CYP3A4 | |
| SCHEMBL14727445 | 0.79 | CHEK2 (0.51) | AVPR1BMEN1LMNACYP1A2CYP3A4 | |
| SCHEMBL2154701 | 0.78 | CHEK2 (0.50) | AVPR1BPARP1ABL1BCR | |
| SCHEMBL14474533 | 0.74 | EGFR (0.51) | AVPR1BMEN1LMNACYP1A2CYP3A4 | |
| SCHEMBL14474103 | 0.73 | CYP1A2 (0.51) | AVPR1BMEN1LMNACYP1A2CYP3A4 | |
| SCHEMBL2154778 | 0.73 | CYP1A2 (0.57) | AVPR1BMEN1LMNACYP1A2CYP3A4 | |
| SCHEMBL2156495 | 0.72 | ABCG2 (0.48) | MEN1LMNACYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102883723-A | Therapeutic compounds and related methods of use | GALENEA CORP | 2013-01-16 | — | — | CN | disclosed |