SCHEMBL2156495

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2154791	0.92	MAPT (0.52)	ABCG2GBA1KDM4EMAPTNPSR1
	SCHEMBL14475410	0.92	ABCG2 (0.51)	ABCG2GBA1KDM4EMAPTNPSR1
	SCHEMBL14731266	0.92	ABCG2 (0.47)	ABCG2GBA1KDM4EMAPTNPSR1
	SCHEMBL14473984	0.91	ABCG2 (0.50)	ABCG2GBA1KDM4EMAPTNPSR1
	SCHEMBL14726046	0.90	ABCG2 (0.51)	ABCG2KDM4EMAPTNPSR1ALDH1A1
	SCHEMBL14727149	0.90	ROCK2 (0.49)	ABCG2GBA1KDM4EMAPTNPSR1
	SCHEMBL20273559	0.90	GBA1 (0.48)	ABCG2GBA1KDM4EMAPTNPSR1
	SCHEMBL14475087	0.89	PDE5A (0.48)	ABCG2GBA1KDM4EMAPTNPSR1
	SCHEMBL14474560	0.89	SIRT2 (0.48)	ABCG2KDM4EMAPTALDH1A1MAPK8
	SCHEMBL14727160	0.89	ABCG2 (0.49)	ABCG2KDM4EMAPTNPSR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.