Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 16/20 | 1.00 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.65 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.63 |
| ▸ | STS | P08842 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31238411 | 0.93 | SIGMAR1 (0.87) | SIGMAR1ABCB1ABCG2KDM4ENPC1 | |
| SCHEMBL8786635 | 0.92 | SIGMAR1 (1.00) | SIGMAR1 | |
| SCHEMBL8786990 | 0.92 | SIGMAR1 (1.00) | SIGMAR1 | |
| SCHEMBL8788283 | 0.92 | SIGMAR1 (1.00) | SIGMAR1 | |
| SCHEMBL8787025 | 0.92 | SIGMAR1 (1.00) | SIGMAR1 | |
| Hydrochloric Acid SCHEMBL8787136 | 0.92 | SIGMAR1 (0.98) | SIGMAR1ABCB1ABCG2 | |
| SCHEMBL8786706 | 0.92 | SIGMAR1 (1.00) | SIGMAR1 | |
| SCHEMBL8787028 | 0.92 | SIGMAR1 (1.00) | SIGMAR1 | |
| Hydrochloric Acid SCHEMBL8788489 | 0.91 | SIGMAR1 (0.98) | SIGMAR1 | |
| SCHEMBL28647889 | 0.86 | SIGMAR1 (0.78) | SIGMAR1ABCB1ABCG2KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103127053-B | Medical application of 6-[2-(dimethylamino)ethoxy]flavone | UNIV SHENYANG PHARMACEUTICAL | 2014-05-21 | — | — | CN | disclosed |
| CN-103127053-B | Medical application of 6-[2-(dimethylamino)ethoxy]flavone | UNIV SHENYANG PHARMACEUTICAL | 2014-05-21 | — | — | CN | disclosed |
| CN-103127053-A | Medical application of 6-[2-(dimethylamino)ethoxy]flavone | UNIV SHENYANG PHARMACEUTICAL | 2013-06-05 | — | — | CN | disclosed |
| CN-103127053-A | Medical application of 6-[2-(dimethylamino)ethoxy]flavone | UNIV SHENYANG PHARMACEUTICAL | 2013-06-05 | — | — | CN | disclosed |