SCHEMBL27904992

SCHEMBL27904992

O=C(Cl)Cl.O=C(Cl)c1cc(Cl)ns1

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SIRT6 Q8N6T7 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27462395 0.98
SCHEMBL19274422 0.80
SCHEMBL28300597 0.78 DAO (0.42)
SCHEMBL27315460 0.78 DAO (0.42)
SCHEMBL27311130 0.78
SCHEMBL27911555 0.77 CA1 (0.34)
SCHEMBL7134538 0.74
SCHEMBL27568917 0.74 ALDH1A1 (0.43)
SCHEMBL6171577 0.59
SCHEMBL1771045 0.59

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103102323-A Process for the production of 3, 4-dichloro-N- (2-cyano-phenyl) -5-isothiazolecarboxamide BAYER CROPSCIENCE AG 2013-05-15 CN claimed
CN-103087003-A Process for the production of 3, 4-dichloro-N- (2-cyano-phenyl) -5-isothiazolecarboxamide BAYER CROPSCIENCE AG 2013-05-08 CN claimed