Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.59 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.42 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.42 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.42 |
| ▸ | HTR7 | P34969 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.39 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.39 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9367 | 0.98 | PAOX (0.55) | PAOXSIGMAR1HRH3GNAI3GNAO1 | |
| SCHEMBL8865 | 0.90 | PAOX (0.52) | PAOXSIGMAR1HRH3USP2ALDH1A1 | |
| SCHEMBL31632710 | 0.87 | PAOX (0.64) | PAOXSIGMAR1HRH3GNAI3GNAO1 | |
| SCHEMBL6659222 | 0.87 | PAOX (0.64) | PAOXSIGMAR1HRH3GNAI3GNAO1 | |
| SCHEMBL31632718 | 0.87 | PAOX (0.64) | PAOXSIGMAR1HRH3GNAI3GNAO1 | |
| SCHEMBL15340848 | 0.87 | PAOX (0.64) | PAOXSIGMAR1HRH3GNAI3GNAO1 | |
| SCHEMBL20234244 | 0.84 | PAOX (0.60) | PAOXSIGMAR1HRH3GNAI3GNAO1 | |
| SCHEMBL6663287 | 0.84 | PAOX (0.60) | PAOXSIGMAR1HRH3GNAI3GNAO1 | |
| SCHEMBL27923836 | 0.84 | GNAI3 (0.45) | PAOXHRH3GNAI3GNAO1GNAI1 | |
| SCHEMBL2974911 | 0.82 | PAOX (0.46) | PAOXSIGMAR1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103153329-A | Use of novel cyclosporin A derivatives for the treatment and prevention of viral infections | S & T GLOBAL INC | 2013-06-12 | — | — | CN | claimed |