SCHEMBL27906357

SCHEMBL27906357

O=C(NCCC(Oc1cccc2ccccc12)c1ccccc1)c1ccccc1

nearest known ligand 0.65

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 15/20 0.65
SLC6A2 P23975 13/20 0.65
EPHX2 P34913 2/20 0.55
KMT2A Q03164 1/20 0.46
HTR1A P08908 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2722680 0.79 SLC6A4 (1.00) SLC6A4SLC6A2KMT2A
SCHEMBL5078702 0.79 SLC6A4 (0.75) SLC6A4SLC6A2KMT2AHTR1A
SCHEMBL8285421 0.79 SLC6A4 (0.69) SLC6A4SLC6A2KMT2A
SCHEMBL28017684 0.74 SLC6A2 (0.68) SLC6A4SLC6A2
SCHEMBL541162 0.74 SLC6A2 (0.68) SLC6A4SLC6A2
SCHEMBL4447884 0.74 SLC6A4 (0.45) SLC6A4SLC6A2
SCHEMBL27310746 0.74 SLC6A2 (0.56) SLC6A4SLC6A2KMT2A
Bromide SCHEMBL6903611 0.73 SLC6A2 (0.66) SLC6A4SLC6A2
Oxalic Acid SCHEMBL3770 0.72 SLC6A4 (0.69) SLC6A4SLC6A2
SCHEMBL5948102 0.72 EPHX2 (1.00) EPHX2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102911065-A Synthesizing method of 5-serotonin reuptake inhibitor ZHU LIANG 2013-02-06 CN disclosed