Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | FPR2 | P25090 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 4/20 | 0.35 |
| ▸ | PER2 | O15055 | 1/20 | 0.35 |
| ▸ | CRY1 | Q16526 | 1/20 | 0.35 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.35 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.35 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.35 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.34 |
| ▸ | CFD | P00746 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | F2R | P25116 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2790206 | 1.00 | PROKR1 (0.42) | PROKR1CNR2FPR2DPP4PER2 | |
| SCHEMBL2790078 | 0.96 | PROKR1 (0.43) | PROKR1CNR2FPR2DPP4PER2 | |
| SCHEMBL2790426 | 0.94 | PROKR1 (0.42) | PROKR1CNR2FPR2DPP4PER2 | |
| SCHEMBL2789741 | 0.94 | PROKR1 (0.41) | PROKR1CNR2FPR2PER2CRY1 | |
| SCHEMBL2790427 | 0.94 | PROKR1 (0.42) | PROKR1CNR2FPR2DPP4PER2 | |
| SCHEMBL2791208 | 0.94 | PROKR1 (0.41) | PROKR1CNR2FPR2DPP4PER2 | |
| SCHEMBL2791207 | 0.94 | PROKR1 (0.41) | PROKR1CNR2FPR2DPP4PER2 | |
| SCHEMBL2792287 | 0.94 | PROKR1 (0.42) | PROKR1CNR2DPP4PER2CRY1 | |
| SCHEMBL2790512 | 0.94 | PROKR1 (0.42) | PROKR1CNR2DPP4PER2CRY1 | |
| SCHEMBL2792324 | 0.94 | PROKR1 (0.42) | PROKR1CNR2DPP4PER2CRY1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111634-A2 | RENIN INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-09-30 | — | — | WO | claimed |
| WO-2010111634-A2 | RENIN INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-09-30 | — | — | WO | disclosed |