Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 2/20 | 0.56 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.56 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.56 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.56 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.56 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.56 |
| ▸ | BRAF | P15056 | 8/20 | 0.51 |
| ▸ | PDE10A | Q9Y233 | 5/20 | 0.48 |
| ▸ | MAPK3 | P27361 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.46 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8489264 | 0.85 | CSNK1D (0.61) | MAPK14MAPK13CSNK1DCSNK1EMAPK12 | |
| SCHEMBL5258671 | 0.81 | MAPK13 (0.71) | MAPK14MAPK13CSNK1DCSNK1EMAPK12 | |
| SCHEMBL29912055 | 0.80 | JMJD6 (0.44) | MAPK14MAPK13CSNK1DCSNK1EMAPK12 | |
| SCHEMBL15022322 | 0.78 | CSNK1D (0.52) | MAPK14MAPK13CSNK1DCSNK1EMAPK12 | |
| SCHEMBL27540656 | 0.78 | MAPK13 (0.59) | MAPK14MAPK13CSNK1DCSNK1EMAPK12 | |
| SCHEMBL29911729 | 0.78 | IRAK4 (0.47) | MAPK14MAPK13CSNK1DCSNK1EMAPK12 | |
| SCHEMBL25263176 | 0.77 | MAPK13 (0.66) | MAPK14MAPK13CSNK1DCSNK1EMAPK12 | |
| SCHEMBL15022080 | 0.75 | PDE10A (0.49) | MAPK14MAPK13CSNK1DCSNK1EMAPK12 | |
| SCHEMBL15735061 | 0.75 | PDE10A (0.64) | MAPK14MAPK13CSNK1DCSNK1EMAPK12 | |
| SCHEMBL30123648 | 0.75 | PDE10A (0.64) | MAPK14MAPK13CSNK1DCSNK1EMAPK12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103159738-A | Mixed aromatic compound of alkynyl bridging and application thereof | SHANGHAI HONGBO ZHIYUAN MEDICAL TECHNOLOGY CO LTD | 2013-06-19 | — | — | CN | disclosed |