Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 4/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11252426 | 0.78 | HTR2A (0.42) | AOC3HTR2AHRH1SLC6A2SLC6A4 | |
| SCHEMBL6834936 | 0.78 | LMNA (0.50) | AOC3TDP1CYP2C19CYP1A2ALDH1A1 | |
| SCHEMBL723197 | 0.78 | LMNA (0.50) | AOC3TDP1CYP2C19CYP1A2ALDH1A1 | |
| SCHEMBL38652517 | 0.77 | IDO1 (0.43) | SLC6A2SLC6A4SLC6A3TDP1HSD17B10 | |
| SCHEMBL29361993 | 0.77 | CYP3A4 (0.41) | AOC3TDP1CYP2C19CYP1A2ALDH1A1 | |
| SCHEMBL10361470 | 0.77 | IDO1 (0.43) | SLC6A2SLC6A4SLC6A3TDP1HSD17B10 | |
| SCHEMBL3940465 | 0.77 | CYP3A4 (0.41) | AOC3TDP1CYP2C19CYP1A2ALDH1A1 | |
| SCHEMBL4575144 | 0.77 | AOC3 (0.46) | AOC3HTR2AHRH1SLC6A2SLC6A4 | |
| SCHEMBL1205121 | 0.77 | AOC3 (0.46) | AOC3HTR2AHRH1SLC6A2SLC6A4 | |
| SCHEMBL27483744 | 0.77 | HTT (0.42) | AOC3HTR2AHRH1SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103153063-A | Quinoline derivatives and MELK inhibitors containing the same | ONCOTHERAPY SCIENCE INC | 2013-06-12 | — | — | CN | disclosed |