Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 20/20 | 0.66 |
| ▸ | HTR2A | P28223 | 20/20 | 0.66 |
| ▸ | DRD3 | P35462 | 20/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27907782 | 1.00 | DRD2 (0.66) | DRD2HTR2ADRD3 | |
| SCHEMBL15385225 | 0.85 | DRD2 (0.77) | DRD2HTR2ADRD3 | |
| SCHEMBL14874306 | 0.85 | DRD2 (0.77) | DRD2HTR2ADRD3 | |
| SCHEMBL27891011 | 0.83 | DRD2 (0.66) | DRD2HTR2ADRD3 | |
| SCHEMBL27907801 | 0.83 | DRD2 (0.66) | DRD2HTR2ADRD3 | |
| SCHEMBL1698385 | 0.81 | DRD2 (0.78) | DRD2HTR2ADRD3 | |
| SCHEMBL15385196 | 0.81 | DRD2 (0.78) | DRD2HTR2ADRD3 | |
| SCHEMBL27894977 | 0.80 | DRD2 (0.49) | DRD2HTR2ADRD3 | |
| SCHEMBL27894978 | 0.80 | DRD2 (0.49) | DRD2HTR2ADRD3 | |
| SCHEMBL12073701 | 0.80 | DRD2 (0.68) | DRD2HTR2ADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102947310-A | Fused pyridine compounds as dual modulators of the 5-HT2A and D3 receptors | HOFFMANN LA ROCHE | 2013-02-27 | — | — | CN | disclosed |