Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K4 | P45985 | 1/20 | 0.55 |
| ▸ | DNMT1 | P26358 | 3/20 | 0.37 |
| ▸ | JAK2 | O60674 | 3/20 | 0.35 |
| ▸ | JAK3 | P52333 | 3/20 | 0.35 |
| ▸ | PTK2 | Q05397 | 3/20 | 0.35 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | MASP2 | O00187 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2634265 | 0.83 | CCR2 (0.38) | MAP2K4DNMT1PDE2APDE4APDE4B | |
| SCHEMBL22801552 | 0.80 | MAP2K4 (0.60) | MAP2K4JAK2JAK3PTK2MAPT | |
| SCHEMBL2634290 | 0.79 | PDE2A (0.40) | DNMT1PDE2AMASP2F2NR1H3 | |
| SCHEMBL15708456 | 0.79 | MAP2K4 (0.61) | MAP2K4MAPTNR1H2GPR119 | |
| SCHEMBL16800427 | 0.78 | MAP2K4 (0.62) | MAP2K4MAPTGPR119 | |
| SCHEMBL14487511 | 0.75 | MAP2K4 (0.57) | MAP2K4JAK2MAPTNR1H2GPR119 | |
| SCHEMBL13736017 | 0.75 | CA12 (0.34) | MAP2K4MAPTNR1H2 | |
| SCHEMBL20402734 | 0.74 | MAP2K4 (0.32) | MAP2K4MAPT | |
| SCHEMBL22801706 | 0.73 | MAP2K4 (0.68) | MAP2K4MAPT | |
| SCHEMBL1513075 | 0.73 | MAP2K4 (0.52) | MAP2K4MAPTGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102933575-A | Yclohexyl-azetidinyl antagonists of ccr2 | JANSSEN PHARMACEUTICA NV | 2013-02-13 | — | — | CN | disclosed |