Triphosphate

Triphosphate

SCHEMBL27909453

Nc1nc2c(ncn2[C@H]2C[C@H](O)[C@@H](COP(=O)(O)O)O2)c(=O)[nH]1.O=P(O)(O)OP(=O)(O)OP(=O)(O)O

nearest known ligand 0.82

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.82
P2RY2 P41231 1/20 0.68
P2RY4 P51582 1/20 0.68
P2RY6 Q15077 1/20 0.68
TGM2 P21980 1/20 0.57
NT5E P21589 2/20 0.56
FUT5 Q11128 1/20 0.55
KRAS P01116 2/20 0.54
PNP P00491 1/20 0.54
POLG P54098 1/20 0.53
TAS1R3 Q7RTX0 2/20 0.52
TAS1R1 Q7RTX1 2/20 0.52
IMPDH2 P12268 4/20 0.51
IMPDH1 P20839 1/20 0.51
ENPP1 P22413 1/20 0.51
P2RY1 P47900 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2219689 0.96 POLB (0.82) POLBP2RY2P2RY4P2RY6TGM2
SCHEMBL18785152 0.96 POLB (0.82) POLBP2RY2P2RY4P2RY6TGM2
SCHEMBL18775385 0.96 POLB (0.82) POLBP2RY2P2RY4P2RY6TGM2
SCHEMBL157937 0.96 POLB (0.82) POLBP2RY2P2RY4P2RY6TGM2
SCHEMBL25171429 0.96 POLB (0.82) POLBP2RY2P2RY4P2RY6TGM2
SCHEMBL16678590 0.96 POLB (0.82) POLBP2RY2P2RY4P2RY6TGM2
SCHEMBL18785118 0.96 POLB (0.82) POLBP2RY2P2RY4P2RY6TGM2
SCHEMBL1971161 0.96 POLB (0.82) POLBP2RY2P2RY4P2RY6TGM2
SCHEMBL17117812 0.96 POLB (0.82) POLBP2RY2P2RY4P2RY6TGM2
SCHEMBL48232 0.96 POLB (0.82) POLBP2RY2P2RY4P2RY6TGM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102952887-A Real-time fluorescence PCR (polymerase chain reaction) kit and detection method for detecting Byssochlamys nivea ZHEJIANG QUALITY INSPECTION SCIENCE RES INST 2013-03-06 CN disclosed