SCHEMBL2219689

SCHEMBL2219689

Nc1nc2c(ncn2[C@H]2CC(O)[C@@H](COP(=O)(O)OP(=O)(O)O)O2)c(=O)[nH]1

nearest known ligand 0.82

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.82
P2RY2 P41231 2/20 0.73
P2RY4 P51582 2/20 0.73
P2RY6 Q15077 2/20 0.73
TGM2 P21980 1/20 0.61
FUT5 Q11128 1/20 0.59
KRAS P01116 2/20 0.58
NT5E P21589 2/20 0.56
PNP P00491 1/20 0.56
POLG P54098 1/20 0.55
DTYMK P23919 4/20 0.54
ENPP1 P22413 2/20 0.51
P2RY1 P47900 1/20 0.51
DCPS Q96C86 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18775385 1.00 POLB (0.82) POLBP2RY2P2RY4P2RY6TGM2
SCHEMBL157937 1.00 POLB (0.82) POLBP2RY2P2RY4P2RY6TGM2
SCHEMBL18785152 1.00 POLB (0.82) POLBP2RY2P2RY4P2RY6TGM2
SCHEMBL16699229 0.99 POLB (0.81) POLBP2RY2P2RY4P2RY6TGM2
Deoxyguanosine Triphosphate SCHEMBL2820367 0.99 POLB (0.81) POLBP2RY2P2RY4P2RY6TGM2
Deoxyguanosine Triphosphate SCHEMBL252797 0.99 POLB (0.81) POLBP2RY2P2RY4P2RY6TGM2
SCHEMBL3042901 0.99 POLB (0.81) POLBP2RY2P2RY4P2RY6TGM2
Deoxyguanosine Triphosphate SCHEMBL12729493 0.99 POLB (0.81) POLBP2RY2P2RY4P2RY6TGM2
Deoxyguanosine Triphosphate SCHEMBL18785123 0.99 POLB (0.81) POLBP2RY2P2RY4P2RY6TGM2
Deoxyguanosine Triphosphate SCHEMBL80609 0.99 POLB (0.81) POLBP2RY2P2RY4P2RY6TGM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025072741-A1 PRESERVATIVES FOR MOLECULAR SAMPLE ANALYSIS WITH SAMPLE COLLECTION DEVICES BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2025-04-03 WO claimed
US-20050136673-A1 CMP slurry XU WEN-QING (US) 2005-06-23 US claimed
US-5480980-A DNA SEQUENCES BOEHRINGER MANNHEIM GMBH (DE) 1996-01-02 US claimed
WO-2025072741-A1 PRESERVATIVES FOR MOLECULAR SAMPLE ANALYSIS WITH SAMPLE COLLECTION DEVICES BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2025-04-03 WO disclosed
US-20240241107-A1 SERUM METABOLOMICS RELATED TO CHIMERIC ANTIGEN RECEPTOR (CAR) T-CELL THERAPY BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2024-07-18 US disclosed
EP-4333860-A1 SERUM METABOLOMICS RELATED TO CHIMERIC ANTIGEN RECEPTOR (CAR) T-CELL THERAPY Board of Regents, The University of Texas System (US) 2024-03-13 EP disclosed
WO-2022236131-A1 SERUM METABOLOMICS RELATED TO CHIMERIC ANTIGEN RECEPTOR (CAR) T-CELL THERAPY BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2022-11-10 WO disclosed
US-20170112948-A1 Inorganic-organic hybrid compound Karlsruher Institut für Technologie (DE) 2017-04-27 US disclosed
US-9062392-B2 Methods for isolating a peptide methods for identifying a peptide INTEL CORPORATION (US) 2015-06-23 US disclosed
US-9034659-B2 Biosensors MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2015-05-19 US disclosed
US-20150133305-A1 METHODS FOR ISOLATING A PEPTIDE METHODS FOR IDENTIFYING A PEPTIDE INTEL CORPORATION 2015-05-14 US disclosed
WO-2013022545-A1 HIGH SURFACE AREA FLEXIBLE CHEMIRESISTIVE BIOSENSOR BY OXIDATIVE CHEMICAL VAPOR DEPOSITION MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2013-02-14 WO disclosed
US-20110246081-A1 Metabolomics-Based Identification of Disease-Causing Agents GEORGIA TECH RESEARCH CORPORATION (US) 2011-10-06 US disclosed
US-20110177964-A1 CHEMOSENSORY ARRAYS THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2011-07-21 US disclosed
US-20060252115-A1 Synthesis and use of anti-reverse mRNA cap analogues DARZYNKIEWICZ EDWARD 2006-11-09 US disclosed
US-7074596-B2 Synthesis and use of anti-reverse mRNA cap analogues BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) 2006-07-11 US disclosed
US-20050136673-A1 CMP slurry XU WEN-QING (US) 2005-06-23 US disclosed
US-20050028450-A1 CMP slurry XU WEN-QING (US) 2005-02-10 US disclosed
US-20030194759-A1 Synthesis and use of anti-reverse mRBA cap analogues DARZYNKIEWICZ, EDWARD (PL) 2003-10-16 US disclosed
US-5087565-A Synthetic process for preparation of 32 P-labeled nucleotides DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1992-02-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060252115-A1 Synthesis and use of anti-reverse mRNA cap analogues RNGTT, RNMT, CPSF6 POLB 228/4885P2RY2 2581/4885P2RY4 2153/4885
US-20170112948-A1 Inorganic-organic hybrid compound SLCO4C1, SLCO2A1, SLCO1A2 POLB 3337/4885P2RY2 1037/4885P2RY4 518/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.