Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 2/20 | 0.41 |
| ▸ | PLAU | P00749 | 2/20 | 0.41 |
| ▸ | ELANE | P08246 | 2/20 | 0.41 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.41 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29540947 | 0.85 | MAPT (0.46) | KMT2AMEN1RXFP1CYP19A1ALDH1A1 | |
| SCHEMBL5446082 | 0.85 | MAPT (0.46) | KMT2AMEN1RXFP1CYP19A1ALDH1A1 | |
| SCHEMBL6750910 | 0.85 | GAA (0.46) | KMT2AMEN1RXFP1PKMHTT | |
| SCHEMBL6750905 | 0.84 | CYP19A1 (0.49) | KMT2AMEN1RXFP1PKMCYP19A1 | |
| SCHEMBL6747189 | 0.83 | MEN1 (0.45) | KMT2AMEN1RXFP1PKMCYP19A1 | |
| SCHEMBL27628310 | 0.83 | CYP19A1 (0.45) | KMT2AMEN1RXFP1PKMCYP19A1 | |
| SCHEMBL6482272 | 0.79 | TUBB1 (0.46) | KMT2AMEN1PKMHTTALDH1A1 | |
| SCHEMBL6750946 | 0.78 | MEN1 (0.41) | KMT2AMEN1RXFP1CYP19A1ALDH1A1 | |
| SCHEMBL6490943 | 0.77 | CYP19A1 (0.43) | KMT2AMEN1RXFP1HTTCYP19A1 | |
| SCHEMBL5113851 | 0.77 | KMT2A (0.49) | KMT2AMEN1RXFP1HTTCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102971327-B | There is the anti-inflammatory compound of multiple tyrosine-kinase enzyme inhibition activity and the pharmaceutical compositions containing these compounds | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2016-04-20 | — | — | CN | disclosed |
| CN-102971327-A | Anti-inflammatory compound having inhibitory activity against multiple tyrosine kinases, and pharmaceutical composition containing same | KOREA INST SCI & TECH | 2013-03-13 | — | — | CN | disclosed |