Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | RORC | P51449 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 2/20 | 0.39 |
| ▸ | PLAU | P00749 | 2/20 | 0.39 |
| ▸ | ELANE | P08246 | 2/20 | 0.39 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6480444 | 0.88 | MAPT (0.42) | CYP19A1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL6490326 | 0.88 | RORC (0.44) | CYP19A1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL6482272 | 0.85 | TUBB1 (0.46) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL6494950 | 0.83 | RORC (0.42) | CYP19A1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL6488524 | 0.81 | MAPT (0.40) | CYP19A1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL6750905 | 0.81 | CYP19A1 (0.49) | CYP19A1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL27628310 | 0.80 | CYP19A1 (0.45) | CYP19A1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL6479624 | 0.79 | BRPF1 (0.43) | ALDH1A1LMNASMN1; SMN2TSHRPLAU | |
| SCHEMBL6232382 | 0.78 | AKR1C3 (0.46) | CYP19A1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL6747189 | 0.77 | MEN1 (0.45) | CYP19A1MAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050215614-A1 | Substituted indoles and their use as hcv inhibitors | RIGEL PHARMACEUTICALS, INC. (US) | 2005-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050215614-A1 | Substituted indoles and their use as hcv inhibitors | IDO1, IDO2, HAVCR2 | CYP19A1 1340/4885MAPT 3587/4885ALDH1A1 411/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.