Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Carbamoylcholine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 known ✓ | P20309 | 6/20 | 1.00 |
| ▸ | CHRM5 | P08912 | 6/20 | 1.00 |
| ▸ | CHRM1 | P11229 | 6/20 | 1.00 |
| ▸ | CHRM2 | P08172 | 5/20 | 1.00 |
| ▸ | CHRM4 | P08173 | 5/20 | 1.00 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.95 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.95 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.95 |
| ▸ | HTR1A | P08908 | 2/20 | 0.95 |
| ▸ | LMNA | P02545 | 2/20 | 0.95 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.95 |
| ▸ | TSHR | P16473 | 1/20 | 0.95 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | BLM | P54132 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.60 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.60 |
| ▸ | PGR | P06401 | 1/20 | 0.60 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.60 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carbamoylcholine SCHEMBL5060882 | 1.00 | CHRM5 (1.00) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| Carbamoylcholine SCHEMBL21197429 | 0.98 | CHRM5 (0.95) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| Carbamoylcholine SCHEMBL10770841 | 0.98 | CHRM5 (0.95) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| Carbamoylcholine SCHEMBL10692446 | 0.98 | CHRM5 (0.95) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| Carbamoylcholine SCHEMBL547970 | 0.98 | CHRM5 (0.95) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| Carbamoylcholine SCHEMBL9109254 | 0.98 | CHRM5 (0.95) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| Carbamoylcholine SCHEMBL15094513 | 0.98 | CHRM5 (0.95) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| Carbamoylcholine SCHEMBL2792 | 0.98 | CHRM1 (1.00) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| Carbamoylcholine SCHEMBL2406725 | 0.98 | CHRM1 (1.00) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| Carbamoylcholine SCHEMBL27544830 | 0.96 | CHRM5 (0.91) | CHRM5CHRM1CHRM3CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 24143 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4739302-A2 | HYALURONIC ACID BASED DRUG DELIVERY SYSTEMS | Cella Therapeutics, LLC (US) | 2026-05-13 | — | — | EP | claimed |
| EP-4736841-A1 | A MUCOADHESIVE LAYER FOR BUCCAL ADMINISTRATION OF AN ACTIVE PHARMACEUTICAL INGREDIENT | IQ medical GmbH (DE) | 2026-05-06 | — | — | EP | claimed |
| EP-4734844-A1 | PHYSICOCHEMICAL-SENSING ELECTRONIC SKIN FOR STRESS RESPONSE MONITORING | California Institute of Technology (US) | 2026-05-06 | — | — | EP | claimed |
| EP-4736853-A2 | DEGRADANT COMPOUND IN A MEDICAMENT | Visus Therapeutics, Inc. (US) | 2026-05-06 | — | — | EP | claimed |
| US-12606797-B2 | Methods of detection of mechanically-activated platelet activation and uses thereof | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2026-04-21 | — | — | US | claimed |
| EP-4724079-A2 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF AGE-RELATED MACULAR DEGENERATION | Stealth BioTherapeutics Inc. (US) | 2026-04-15 | — | — | EP | claimed |
| US-20260090984-A1 | CONTACT LENSES INCLUDING MEDICAMENTS AND METHODS OF MAKING AND USING SAME INCLUDING SLOW RELEASE OF GLAUCOMA TREATING DRUGS AND COMFORT ENHANCING DRUGS | MEDIPRINT OPHTHALMICS INC. (US) | 2026-04-02 | — | — | US | claimed |
| US-12590297-B2 | Differentiation method | KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN (NL) | 2026-03-31 | — | — | US | claimed |
| US-20260083698-A1 | Synergistic Stimulation of Mucociliary Clearance to Treat Mucus Obstruction in Cystic Fibrosis and Other Muco-Obstructive Disorders | UNIV LELAND STANFORD JUNIOR (US) | 2026-03-26 | — | — | US | claimed |
| US-20260069533-A1 | METHODS FOR THE TREATMENT OF PRESBYOPIA | LENZ THERAPEUTICS OPERATIONS INC (US) | 2026-03-12 | — | — | US | claimed |
| US-4186184-A | Selective administration of drug with ocular therapeutic system | ALZA CORPORATION (US) | 1980-01-29 | — | — | US | claimed |
| US-4138300-A | Process for producing a transparent shaped polymeric product | JAPAN ATOMIC ENERGY RESEARCH INSTITUTE (JP) | 1979-02-06 | — | — | US | claimed |
| US-4136178-A | POTENTIATION OF OPHTHALMIC DRUG | AMERICAN HOME PRODUCTS CORP. (US) | 1979-01-23 | — | — | US | claimed |
| US-4136177-A | FOR TOPICAL OPHTHALMIC USE, DRUG POTENTIATORS | AMERICAN HOME PRODUCTS CORP. (US) | 1979-01-23 | — | — | US | claimed |
| US-4136173-A | VEHICLES FOR OPHTHALMIC DRUGS | AMERICAN HOME PRODUCTS CORP. (US) | 1979-01-23 | — | — | US | claimed |
| US-4115544-A | DRUG PARTICLES MIXED WITH RELEASE RATE-CONTROLLING HOMOPOLYMER | ALZA CORPORATION (US) | 1978-09-19 | — | — | US | claimed |
| US-4014335-A | Ocular drug delivery device | ALZA CORPORATION (US) | 1977-03-29 | — | — | US | claimed |
| US-4014334-A | Laminated osmotic system for dispensing beneficial agent | ALZA CORPORATION (US) | 1977-03-29 | — | — | US | claimed |
| US-4008719-A | Osmotic system having laminar arrangement for programming delivery of active agent | ALZA CORPORATION (US) | 1977-02-22 | — | — | US | claimed |
| US-4001388-A | POLYESTERS | ALZA CORPORATION (US) | 1977-01-04 | — | — | US | claimed |