Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.72 |
| ▸ | TP53 | P04637 | 1/20 | 0.66 |
| ▸ | TSHR | P16473 | 1/20 | 0.66 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.64 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.64 |
| ▸ | FAAH | O00519 | 6/20 | 0.63 |
| ▸ | RARB | P10826 | 3/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL29380777 | 0.92 | LTA4H (0.68) | LTA4HTP53TSHRPLA2G4BFAAH | |
| Bicarbonate SCHEMBL28258920 | 0.92 | LTA4H (0.71) | LTA4HTP53TSHRKCNA3PLA2G4B | |
| SCHEMBL369785 | 0.92 | LTA4H (0.84) | LTA4HTP53TSHRKCNA3FAAH | |
| Propionic Acid SCHEMBL10695788 | 0.91 | LTA4H (0.66) | LTA4HTP53TSHRPLA2G4BFAAH | |
| Formaldehyde SCHEMBL27413966 | 0.90 | LTA4H (0.75) | LTA4HTP53TSHRKCNA3PLA2G4B | |
| SCHEMBL243437 | 0.90 | LTA4H (0.81) | LTA4HTP53TSHRKCNA3PLA2G4B | |
| SCHEMBL9342022 | 0.90 | LTA4H (0.81) | LTA4HTP53TSHRKCNA3PLA2G4B | |
| SCHEMBL197384 | 0.90 | LTA4H (0.81) | LTA4HTP53TSHRKCNA3PLA2G4B | |
| SCHEMBL10341451 | 0.90 | LTA4H (0.81) | LTA4HTP53TSHRKCNA3FAAH | |
| SCHEMBL325289 | 0.90 | LTA4H (0.81) | LTA4HTP53TSHRKCNA3PLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102918701-B | Polyether functionalized redox shuttle additives for lithium ion batteries | U芝加哥阿尔贡股份有限公司 | 2017-05-03 | — | — | CN | disclosed |
| CN-103553886-A | Polyether-functionalized redox shuttle additives for lithium ion batteries | UCHICAGO ARGONNE LLC | 2014-02-05 | — | — | CN | disclosed |
| CN-102918701-A | Polyether functionalized redox shuttle additives for lithium ion batteries | UCHICAGO ARGONNE LLC | 2013-02-06 | — | — | CN | disclosed |