Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tert-Butyl Formate SCHEMBL27911785 | 1.00 | MAPT (0.46) | MAPTALDH1A1LMNAALOX12NPSR1 | |
| SCHEMBL2681976 | 0.89 | MAPT (0.55) | MAPTALDH1A1LMNAALOX12NPSR1 | |
| SCHEMBL2681979 | 0.89 | MAPT (0.55) | MAPTALDH1A1LMNAALOX12NPSR1 | |
| Tert-Butyl Formate SCHEMBL27911774 | 0.83 | HTR2C (0.41) | HTR2AHTR2CKCNH2 | |
| Tert-Butyl Formate SCHEMBL27911775 | 0.83 | HTR2C (0.41) | HTR2AHTR2CKCNH2 | |
| Tert-Butyl Formate SCHEMBL27729961 | 0.83 | MAPT (0.56) | MAPTALDH1A1LMNAALOX12NPSR1 | |
| Tert-Butyl Formate SCHEMBL27747676 | 0.81 | HTR2C (0.46) | MAPTALDH1A1LMNASGPL1HPGD | |
| SCHEMBL7372558 | 0.78 | MAPT (0.43) | MAPTALDH1A1LMNAALOX12NPSR1 | |
| Tert-Butyl Formate SCHEMBL27791266 | 0.76 | HTT (0.36) | ALDH1A1HTR2AHTR2CKCNH2KMT2A | |
| SCHEMBL31045855 | 0.74 | KCNH2 (0.43) | MAPTCYP1A2HTR2CKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103946220-A | Inhibitors of baculovirus containing fragment {2- [4- (biphenyl-4-yl) -1H-imidazol-2-yl ] pyrrolidine-1-carbonylmethyl } amine | THERAVANCE INC | 2014-07-23 | — | — | CN | disclosed |
| CN-103189371-A | Novel hepatitis c virus inhibitors | THERAVANCE INC | 2013-07-03 | — | — | CN | disclosed |