Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.51 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAP4K3 | Q8IVH8 | 3/20 | 0.42 |
| ▸ | HPGDS | O60760 | 2/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.37 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 3/20 | 0.36 |
| ▸ | HTR1A | P08908 | 5/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MLYCD | O95822 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28337315 | 0.90 | CHRNB2 (0.39) | CHRNB2CHRNA4MAP4K3NPC1RAB9A | |
| SCHEMBL4677044 | 0.79 | CHRNB2 (0.53) | CHRNB2CHRNA4MEN1KMT2AMAP4K3 | |
| SCHEMBL12879439 | 0.74 | CHRNB2 (0.48) | CHRNB2CHRNA4MEN1KMT2AMAP4K3 | |
| SCHEMBL17151793 | 0.70 | MAP4K3 (0.48) | CHRNB2CHRNA4MAP4K3TLR9TLR8 | |
| SCHEMBL27742532 | 0.69 | CHRNB2 (0.50) | CHRNB2CHRNA4MAP4K3TLR9TLR8 | |
| SCHEMBL20809193 | 0.69 | CHRNB2 (0.46) | CHRNB2CHRNA4MEN1KMT2AMAP4K3 | |
| Hydrochloric Acid SCHEMBL20135187 | 0.68 | CHRNB2 (0.46) | CHRNB2CHRNA4MEN1KMT2AMAP4K3 | |
| SCHEMBL29786817 | 0.66 | KDR (0.46) | CHRNB2CHRNA4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL14314252 | 0.66 | MEN1 (0.42) | CHRNB2CHRNA4MEN1KMT2AMAP4K3 | |
| SCHEMBL17578452 | 0.66 | TLR9 (0.47) | CHRNB2CHRNA4MAP4K3TLR9TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103228633-A | Heterocyclic compounds as DGAT1 inhibitors | PIRAMAL LIFE SCIENCES LTD | 2013-07-31 | — | — | CN | claimed |
| CN-103228633-A | Heterocyclic compounds as DGAT1 inhibitors | PIRAMAL LIFE SCIENCES LTD | 2013-07-31 | — | — | CN | disclosed |