Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | GRK6 | P43250 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3853251 | 0.90 | ALDH1A1 (0.42) | KDM4EALDH1A1ADORA3LMNARECQL | |
| SCHEMBL3849583 | 0.89 | SMN1; SMN2 (0.48) | KDM4EALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL3848493 | 0.89 | ALDH1A1 (0.43) | KDM4EALDH1A1ADORA3LMNAMAPK1 | |
| SCHEMBL3854700 | 0.86 | MAPK1 (0.50) | KDM4EALDH1A1ADORA3MAPK1SMN1; SMN2 | |
| SCHEMBL27895958 | 0.79 | KDM4E (0.47) | KDM4EALDH1A1LMNAMAPK1RECQL | |
| SCHEMBL3846045 | 0.79 | ALDH1A1 (0.45) | KDM4EALDH1A1ADORA3MAPK1ADORA1 | |
| SCHEMBL3849218 | 0.79 | SMN1; SMN2 (0.45) | KDM4EALDH1A1ADORA3LMNAMAPK1 | |
| SCHEMBL3849163 | 0.79 | PTGDR2 (0.50) | KDM4EALDH1A1ADORA3MAPK1ADORA1 | |
| SCHEMBL4575033 | 0.76 | ALDH1A1 (0.36) | KDM4EALDH1A1ADORA3LMNAOPRM1 | |
| SCHEMBL3845837 | 0.74 | ALDH1A1 (0.43) | KDM4EALDH1A1ADORA3LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101626685-B | N-substituted glycine derivatives: hydroxylase inhibitors | SMITHKLINE BEECHAM CORP | 2013-03-13 | — | — | CN | disclosed |