Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 7/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | P2RX7 | Q99572 | 6/20 | 0.50 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.48 |
| ▸ | PPARG | P37231 | 2/20 | 0.47 |
| ▸ | GRK3 | P35626 | 2/20 | 0.47 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.47 |
| ▸ | PRKCG | P05129 | 1/20 | 0.47 |
| ▸ | PRKCB | P05771 | 1/20 | 0.47 |
| ▸ | PRKCA | P17252 | 1/20 | 0.47 |
| ▸ | PRKCH | P24723 | 1/20 | 0.47 |
| ▸ | GRK2 | P25098 | 1/20 | 0.47 |
| ▸ | GRK5 | P34947 | 1/20 | 0.47 |
| ▸ | PRKCI | P41743 | 1/20 | 0.47 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.47 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.47 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.47 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.47 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27913562 | 0.83 | P2RX7 (0.50) | EPHX2P2RX7ROCK2PPARGGRK3 | |
| SCHEMBL27914101 | 0.83 | P2RX7 (0.47) | EPHX2P2RX7ROCK2PRKCAGRK2 | |
| SCHEMBL27931932 | 0.81 | KMT2A (0.52) | KMT2AEPHX2L3MBTL1ROCK2PPARG | |
| SCHEMBL2714842 | 0.80 | GRK2 (0.55) | EPHX2P2RX7PPARGGRK2 | |
| SCHEMBL3294867 | 0.79 | P2RX7 (0.57) | EPHX2P2RX7 | |
| SCHEMBL27913629 | 0.78 | CD38 (0.47) | P2RX7 | |
| SCHEMBL2717051 | 0.78 | EPHX2 (0.49) | EPHX2P2RX7PPARGGRK2 | |
| SCHEMBL2717522 | 0.78 | SCN9A (0.51) | EPHX2P2RX7PPARGGRK2 | |
| SCHEMBL30252237 | 0.77 | P2RX7 (0.56) | EPHX2P2RX7 | |
| SCHEMBL1568699 | 0.77 | NAMPT (0.69) | KMT2AL3MBTL1ROCK2PRKCGPRKCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103249721-A | Arylamine Derivatives as TTX-S Blockers | RAQUALIA PHARMA INC | 2013-08-14 | — | — | CN | claimed |
| CN-103249721-A | Arylamine Derivatives as TTX-S Blockers | RAQUALIA PHARMA INC | 2013-08-14 | — | — | CN | disclosed |