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Sugi Predict / Compounds / SCHEMBL279157

SCHEMBL279157

SCHEMBL279157

C(=C(c1ccccc1)c1ccccc1)c1ccc(N(c2ccc(SCC3CO3)cc2)c2ccc(SCC3CO3)cc2)cc1

nearest known ligand 0.36

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ CYP19A1 P11511 2/20 0.36
▸ CYP11B2 P19099 2/20 0.36
▸ PTGS2 P35354 4/20 0.35
▸ ESR1 P03372 2/20 0.34
▸ CYP2D6 P10635 1/20 0.33
▸ DRD4 P21917 2/20 0.33
▸ AKR1C3 P42330 1/20 0.32
▸ AKR1C2 P52895 1/20 0.32
▸ AKR1C1 Q04828 1/20 0.32
▸ ALDH1A1 P00352 1/20 0.31
▸ MAPT P10636 1/20 0.31
▸ MAPK1 P28482 1/20 0.31
▸ RAB9A P51151 1/20 0.31
▸ L3MBTL1 Q9Y468 1/20 0.31
▸ ESR2 Q92731 1/20 0.30
▸ NR3C2 P08235 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9608862 1.00 CYP19A1 (0.36) CYP19A1CYP11B2PTGS2ESR1CYP2D6
SCHEMBL279272 0.81 CYP19A1 (0.39) CYP19A1CYP11B2PTGS2ESR1CYP2D6
SCHEMBL278983 0.78 CYP19A1 (0.36) CYP19A1CYP11B2PTGS2ESR1CYP2D6
SCHEMBL278979 0.77 TSHR (0.44) CYP19A1CYP11B2PTGS2ESR1CYP2D6
SCHEMBL2210133 0.77 CYP19A1 (0.57) CYP19A1CYP11B2PTGS2ESR1CYP2D6
SCHEMBL133557 0.75 CYP19A1 (0.55) CYP19A1CYP11B2PTGS2ESR1CYP2D6
SCHEMBL10128938 0.75 CYP19A1 (0.55) CYP19A1CYP11B2PTGS2ESR1CYP2D6
SCHEMBL14018365 0.75 CYP19A1 (0.55) CYP19A1CYP11B2PTGS2ESR1CYP2D6
SCHEMBL6032733 0.75 CYP19A1 (0.55) CYP19A1CYP11B2PTGS2ESR1CYP2D6
SCHEMBL7570019 0.75 CYP19A1 (0.55) CYP19A1CYP11B2PTGS2ESR1CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8426093-B2 photosensitive layer has a charge transferring compound having hole transportation ability; hardening by heating, stable electrical properties FUJI XEROX CO., LTD. (JP) 2013-04-23 — — US disclosed
US-8426093-B2 photosensitive layer has a charge transferring compound having hole transportation ability; hardening by heating, stable electrical properties FUJI XEROX CO., LTD. (JP) 2013-04-23 — — US disclosed
US-8273517-B2 Method of manufacturing electrophotographic photoreceptor, electrophotographic photoreceptor, image-forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2012-09-25 — — US disclosed
US-8263299-B2 Multilayer; electroconductive support, photosensitive layer of cured phenolic resin having dynamics hardness and elastic deformation; xerography;thin film with few defects;mechanical strength; stability; high quality images FUJI XEROX CO., LTD. (JP) 2012-09-11 — — US disclosed
US-8263299-B2 Multilayer; electroconductive support, photosensitive layer of cured phenolic resin having dynamics hardness and elastic deformation; xerography;thin film with few defects;mechanical strength; stability; high quality images FUJI XEROX CO., LTD. (JP) 2012-09-11 — — US disclosed
US-20120134713-A1 METHOD OF MANUFACTURING ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE-FORMING APPARATUS, AND PROCESS CARTRIDGE FUJI XEROX CO., LTD. (JP) 2012-05-31 — — US disclosed
US-8133645-B2 Method of manufacturing electrophotographic photoreceptor, electrophotographic photoreceptor, image-forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2012-03-13 — — US disclosed
US-8133645-B2 Method of manufacturing electrophotographic photoreceptor, electrophotographic photoreceptor, image-forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2012-03-13 — — US disclosed
US-8110328-B2 Conductive support with photosensitive layer containing curable resin, fluorinated surfactants and charge transfer compound FUJI XEROX CO., LTD. (JP) 2012-02-07 — — US disclosed
US-8110328-B2 Conductive support with photosensitive layer containing curable resin, fluorinated surfactants and charge transfer compound FUJI XEROX CO., LTD. (JP) 2012-02-07 — — US disclosed
US-20080102389-A1 Electrophotographic photoreceptor, method of producing the same, process cartridge, and image-forming apparatus FUJI XEROX CO., LTD. (JP) 2008-05-01 — — US disclosed
US-20080089712-A1 Image forming apparatus and process cartridge FUJI XEROX CO., LTD. (JP) 2008-04-17 — — US disclosed
US-20080089712-A1 Image forming apparatus and process cartridge FUJI XEROX CO., LTD. (JP) 2008-04-17 — — US disclosed
US-20080031642-A1 Electrophotographic photoreceptor, image forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2008-02-07 — — US disclosed
US-20080031642-A1 Electrophotographic photoreceptor, image forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2008-02-07 — — US disclosed
US-20070231721-A1 Electrophotographic photoreceptor, process cartridge, image forming apparatus and coating composition FUJI XEROX CO., LTD. (JP) 2007-10-04 — — US disclosed
US-20070231721-A1 Electrophotographic photoreceptor, process cartridge, image forming apparatus and coating composition FUJI XEROX CO., LTD. (JP) 2007-10-04 — — US disclosed
US-20070065741-A1 Electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2007-03-22 — — US disclosed
US-20070065741-A1 Electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2007-03-22 — — US disclosed
US-20070003850-A1 Curable resin composition, electrophotographic photoreceptor, process cartridge, and image-forming apparatus FUJI XEROX CO., LTD. (JP) 2007-01-04 — — US disclosed