Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27915595 | 0.93 | PTGS2 (0.52) | PTGS2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL28805345 | 0.92 | SMN1; SMN2 (0.42) | PTGS2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL27934239 | 0.86 | PTGS2 (0.53) | PTGS2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL27934237 | 0.84 | PTGS2 (0.43) | PTGS2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL27934250 | 0.81 | PDE10A (0.52) | PTGS2PDE10AMAPTL3MBTL1MAPK14 | |
| SCHEMBL27820750 | 0.81 | PTGS2 (0.64) | PTGS2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL27915575 | 0.80 | PTGS2 (0.52) | PTGS2PDE10AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL27934232 | 0.79 | PTGS2 (0.55) | PTGS2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL27915711 | 0.78 | PTGS2 (0.42) | PTGS2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL30023059 | 0.78 | PTGS2 (0.68) | PTGS2HDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102190625-B | Stilbene tumor targeted medicine Combretastatin A4 analogs | NANJING SANHOME PHARMACEUTICAL CO LTD | 2013-08-28 | — | — | CN | disclosed |