Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 7/20 | 0.66 |
| ▸ | GPR35 | Q9HC97 | 7/20 | 0.58 |
| ▸ | MAOB | P27338 | 3/20 | 0.54 |
| ▸ | MAOA | P21397 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA3 | P07451 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | CA6 | P23280 | 1/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27934335 | 0.99 | CNR2 (0.65) | CNR2GPR35MAOBMAOATP53 | |
| SCHEMBL28805354 | 0.96 | CNR2 (0.66) | CNR2GPR35MAOBMAOATP53 | |
| SCHEMBL28807108 | 0.93 | GPR35 (0.60) | CNR2GPR35MAOBMAOATP53 | |
| SCHEMBL27934310 | 0.83 | CNR2 (0.69) | CNR2GPR35MAOACA12CA1 | |
| SCHEMBL27934337 | 0.82 | CNR2 (0.53) | CNR2GPR35CA12CA1CA2 | |
| SCHEMBL27915777 | 0.82 | GPR35 (0.54) | CNR2GPR35MAOBCA12CA1 | |
| SCHEMBL27934287 | 0.82 | CNR2 (0.53) | CNR2GPR35MAOACA12CA1 | |
| SCHEMBL27915779 | 0.82 | CNR2 (0.67) | CNR2GPR35MAOACA12CA1 | |
| SCHEMBL27915782 | 0.81 | CNR2 (0.52) | CNR2GPR35MAOBCA12CA1 | |
| SCHEMBL27915778 | 0.80 | CNR2 (0.50) | CNR2GPR35CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103265517-A | 3-substituted coumarin derivative and use thereof | UNIV ZHEJIANG | 2013-08-28 | — | — | CN | disclosed |