Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Ether. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | TSHR | P16473 | 6/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | PPARD | Q03181 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ether SCHEMBL11081 | 0.96 | — | — | |
| Ether SCHEMBL188032 | 0.96 | ALDH1A1 (0.62) | ALDH1A1TSHRMAPK1MEN1KMT2A | |
| Ether SCHEMBL118077 | 0.96 | ALDH1A1 (0.62) | ALDH1A1TSHRMAPK1MEN1KMT2A | |
| Ether SCHEMBL10536028 | 0.96 | ALDH1A1 (0.62) | ALDH1A1TSHRMAPK1MEN1KMT2A | |
| Ether SCHEMBL8943279 | 0.96 | ALDH1A1 (0.62) | ALDH1A1TSHRMAPK1MEN1KMT2A | |
| Ether SCHEMBL10757495 | 0.93 | ALDH1A1 (0.53) | ALDH1A1TSHRMAPK1MEN1KMT2A | |
| Ether SCHEMBL10576906 | 0.92 | ALDH1A1 (0.59) | ALDH1A1TSHRMAPK1MEN1KMT2A | |
| Ether SCHEMBL557752 | 0.92 | ALDH1A1 (0.59) | ALDH1A1TSHRMAPK1MEN1KMT2A | |
| Ether SCHEMBL11640883 | 0.92 | ALDH1A1 (0.59) | ALDH1A1TSHRMAPK1MEN1KMT2A | |
| Ether SCHEMBL18263650 | 0.92 | ALDH1A1 (0.59) | ALDH1A1TSHRMAPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 6655 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024142112-A1 | CROP NUTRITION AND FORTIFICATION COMPOSITION | BHUKHANWALA KOMAL (IN) | 2024-07-04 | — | — | WO | claimed |
| US-20230383105-A1 | Microporous Membrane With Enhanced Electrolyte Wettability | CELANESE INTERNATIONAL CORPORATION | 2023-11-30 | — | — | US | claimed |
| EP-4237481-A1 | MICROPOROUS MEMBRANE WITH ENHANCED ELECTROLYTE WETTABILITY | Celanese International Corporation (US) | 2023-09-06 | — | — | EP | claimed |
| CN-116710512-A | Microporous films with enhanced electrolyte wettability | 国际人造丝公司 | 2023-09-05 | — | — | CN | claimed |
| WO-2022087889-A1 | MICROPOROUS MEMBRANE WITH ENHANCED ELECTROLYTE WETTABILITY | CELANESE INTERNATIONAL CORPORATION (US) | 2022-05-05 | — | — | WO | claimed |
| CN-110549985-B | Low-air-permeability one-step-formed safety airbag and production process thereof | 华懋（厦门）新材料科技股份有限公司 | 2021-02-09 | — | — | CN | claimed |
| CN-110549985-A | Low-air-permeability one-step-formed safety airbag and production process thereof | HMT XIAMEN NEW TECHNICAL MAT CO LTD | 2019-12-10 | — | — | CN | claimed |
| EP-2045393-B2 | Method for manufacturing an abrasion resistant film and finishing film manufactured according to this method | DAKOR MELAMIN IMPRAEGNIERUNGEN GMBH (DE) | 2019-11-20 | — | — | EP | claimed |
| CN-105828881-B | Reduce the oxidation dye of hair damages | 汉高股份有限及两合公司 | 2019-04-30 | — | — | CN | claimed |
| EP-3082962-B1 | OXIDATION DYE WITH REDUCED HAIR DAMAGE | HENKEL AG & CO KGAA (DE) | 2019-02-06 | — | — | EP | claimed |
| EP-0711747-B1 | Esterification process | UNION CARBIDE CHEM PLASTIC (US) | 1998-07-29 | — | — | EP | claimed |
| US-5691300-A | CONTAINING A FATTY ACID N-ALKYL POLYHYDROXYALKYL AMIDES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1997-11-25 | — | — | US | claimed |
| US-5618973-A | PRODUCING GLYCOL ETHER ESTER BY REACTING GLYCOL ETHER ALCOHOL WITH LOWER CARBOXYLIC ACID IN PRESENCE OF LONG CHAIN ALKYL SUBSTITUTED ARYLSULFONIC ACID | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1997-04-08 | — | — | US | claimed |
| CN-1136614-A | Dye assistant product and its use on wool dyeing | CIBA GEIGY CO LTD (CH) | 1996-11-27 | — | — | CN | claimed |
| EP-0711747-A1 | Esterification process | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1996-05-15 | — | — | EP | claimed |
| US-5070149-A | DISCOLORATION INHIBITION, SMOOTHNESS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-12-03 | — | — | US | claimed |
| EP-0209774-B1 | METHOD FOR THE PREPARATION OF VINYL CHLORIDE POLYMERS THAT CAN BE MADE PASTY | HÜLS AKTIENGESELLSCHAFT (DE) | 1990-05-23 | — | — | EP | claimed |
| US-4804728-A | EMULSION OR MICROSUSPENSION POLYMERIZATION USING ALCOHOL GLYCOL ETHER DISPERSANT | HUELS AKTIENGESELLSCHAFT (DE) | 1989-02-14 | — | — | US | claimed |
| US-4618721-A | Process for the preparation of nitrodiphenyl disulfides | CIBA-GEIGY CORPORATION (US) | 1986-10-21 | — | — | US | claimed |
| EP-0197411-A2 | Shear resistant cationic latex | THE GLIDDEN COMPANY (US) | 1986-10-15 | — | — | EP | claimed |