Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 2/20 | 0.34 |
| ▸ | DPP4 | P27487 | 17/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 12/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 10/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 6/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | FAP | Q12884 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | PREP | P48147 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2791666 | 1.00 | CFD (0.34) | CFDDPP4DPP8DPP7DPP9 | |
| SCHEMBL2790905 | 1.00 | CFD (0.34) | CFDDPP4DPP8DPP7DPP9 | |
| SCHEMBL2791724 | 1.00 | CFD (0.34) | CFDDPP4DPP8DPP7DPP9 | |
| SCHEMBL2788359 | 0.95 | CFD (0.33) | CFDDPP4DPP8DPP7DPP9 | |
| SCHEMBL2790418 | 0.94 | CFD (0.35) | CFDDPP4DPP8DPP7DPP9 | |
| SCHEMBL2792440 | 0.91 | CNR2 (0.36) | CFDDPP4DPP8DPP7DPP9 | |
| SCHEMBL2789055 | 0.89 | CFD (0.33) | CFDDPP4DPP8DPP7DPP9 | |
| SCHEMBL7897742 | 0.88 | CFD (0.34) | CFDDPP4DPP8DPP7DPP9 | |
| SCHEMBL7899334 | 0.87 | CFD (0.35) | CFDDPP4DPP8DPP7DPP9 | |
| SCHEMBL2789744 | 0.86 | DPP4 (0.34) | CFDDPP4DPP8DPP7DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111634-A2 | RENIN INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-09-30 | — | — | WO | claimed |
| WO-2010111634-A2 | RENIN INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-09-30 | — | — | WO | disclosed |