Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | PPARD | Q03181 | 2/20 | 0.57 |
| ▸ | PPARA | Q07869 | 2/20 | 0.57 |
| ▸ | TTR | P02766 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | ERN1 | O75460 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.51 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12697047 | 0.92 | SMN1; SMN2 (0.64) | SMN1; SMN2HTTMAPTERN1HDAC1 | |
| SCHEMBL6848908 | 0.83 | SMN1; SMN2 (0.66) | SMN1; SMN2MAPTHPGDL3MBTL1LMNA | |
| SCHEMBL5681720 | 0.81 | ERCC1 (0.69) | SMN1; SMN2ERCC1ERCC4 | |
| SCHEMBL7550210 | 0.81 | SMN1; SMN2 (0.67) | SMN1; SMN2PPARDPPARAHTTERN1 | |
| SCHEMBL24162968 | 0.81 | HPGD (0.70) | SMN1; SMN2MAPTERN1HPGDL3MBTL1 | |
| SCHEMBL582322 | 0.81 | SMN1; SMN2 (0.85) | SMN1; SMN2L3MBTL1LMNAALDH1A1 | |
| SCHEMBL12172996 | 0.79 | HPGD (0.60) | SMN1; SMN2MAPTHPGDL3MBTL1LMNA | |
| SCHEMBL6848785 | 0.79 | HTT (0.83) | HTTMAPTHDAC1HPGDGAA | |
| SCHEMBL5724399 | 0.78 | NPC1 (0.64) | SMN1; SMN2MAPTHPGDGAAALDH1A1 | |
| SCHEMBL30646461 | 0.78 | ERCC1 (0.69) | SMN1; SMN2PPARDPPARAL3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103223302-A | Preparation method of self-assembly covalent cross-linked sodium filter membrane | OCEAN UNIV CHINA | 2013-07-31 | — | — | CN | claimed |
| CN-103223302-A | Preparation method of self-assembly covalent cross-linked sodium filter membrane | OCEAN UNIV CHINA | 2013-07-31 | — | — | CN | disclosed |