Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | PGR | P06401 | 2/20 | 0.47 |
| ▸ | RORA | P35398 | 1/20 | 0.47 |
| ▸ | RORC | P51449 | 1/20 | 0.47 |
| ▸ | RORB | Q92753 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.45 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CXCR4 | P61073 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27899842 | 0.95 | KDM4E (0.51) | KDM4EMCL1HPGDPGRRORA | |
| SCHEMBL27917528 | 0.89 | DYRK1A (0.55) | TP53SMN1; SMN2DYRK1AMAPTHASPIN | |
| SCHEMBL27899812 | 0.87 | MCL1 (0.48) | KDM4EMCL1HPGDHTTLMNA | |
| Bromide SCHEMBL27899810 | 0.86 | MCL1 (0.47) | KDM4EMCL1HPGDHTTLMNA | |
| SCHEMBL27899821 | 0.84 | HASPIN (0.53) | TP53SMN1; SMN2DYRK1AMAPTHASPIN | |
| SCHEMBL27917591 | 0.83 | MCL1 (0.62) | KDM4EMCL1LMNASMN1; SMN2DYRK1A | |
| SCHEMBL17102927 | 0.80 | DYRK1A (0.65) | PGRRORARORCRORBDYRK1A | |
| SCHEMBL27992434 | 0.80 | PGR (0.52) | KDM4EMCL1HPGDPGRRORA | |
| SCHEMBL28075295 | 0.80 | MCL1 (0.54) | KDM4EMCL1PGRRORARORC | |
| SCHEMBL27908745 | 0.80 | PGR (0.49) | KDM4EMCL1PGRRORARORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114191432-A | Application of harmine derivative in preparation of anti-hydatid insecticide | 新疆医科大学第一附属医院 | 2022-03-18 | — | — | CN | claimed |
| CN-114191432-A | Application of harmine derivative in preparation of anti-hydatid insecticide | 新疆医科大学第一附属医院 | 2022-03-18 | — | — | CN | disclosed |
| CN-104755078-A | Application of harmine derivatives in preparation of antimicrobial agents | XINJIANG HUASHIDAN PHARMACEUTICAL RES CO LTD | 2015-07-01 | — | — | CN | disclosed |
| CN-103070862-A | Application of harmine derivative in preparation of antibacterial drugs | XINJIANG HUASHIDAN PHARMACEUTICAL RES CO LTD | 2013-05-01 | — | — | CN | disclosed |