Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 5/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27917591 | 0.92 | MCL1 (0.62) | MCL1MEN1KMT2ACYP19A1LMNA | |
| SCHEMBL27917518 | 0.89 | MCL1 (0.56) | MCL1MEN1TSHRKMT2ALMNA | |
| SCHEMBL27899816 | 0.85 | P2RX4 (0.52) | MCL1KMT2ACYP19A1LMNAKDM4E | |
| SCHEMBL27992445 | 0.83 | MCL1 (0.60) | MCL1MEN1TSHRKMT2ACYP19A1 | |
| SCHEMBL1739552 | 0.82 | FABP4 (0.45) | MCL1MEN1TSHRKMT2ALMNA | |
| SCHEMBL31402873 | 0.81 | MCL1 (0.58) | MCL1MEN1TSHRKMT2ALMNA | |
| Hydrochloric Acid SCHEMBL1736627 | 0.81 | FABP4 (0.44) | MCL1MEN1TSHRKMT2ALMNA | |
| SCHEMBL27899812 | 0.81 | MCL1 (0.48) | MCL1MEN1KMT2ACYP19A1LMNA | |
| SCHEMBL27992449 | 0.81 | MCL1 (0.63) | MCL1MEN1TSHRKMT2ACYP19A1 | |
| Bromide SCHEMBL27899810 | 0.80 | MCL1 (0.47) | MCL1MEN1KMT2ACYP19A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103070862-A | Application of harmine derivative in preparation of antibacterial drugs | XINJIANG HUASHIDAN PHARMACEUTICAL RES CO LTD | 2013-05-01 | — | — | CN | disclosed |