Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 2/20 | 0.31 |
| ▸ | PARP1 | P09874 | 2/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.31 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 2/20 | 0.30 |
| ▸ | HTR2A | P28223 | 2/20 | 0.30 |
| ▸ | DRD3 | P35462 | 2/20 | 0.30 |
| ▸ | PLK1 | P53350 | 1/20 | 0.30 |
| ▸ | PLK2 | Q9NYY3 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1663977 | 0.83 | SMYD3 (0.39) | HPGDSSMYD3MAPTRAB9ANPC1 | |
| SCHEMBL27937008 | 0.75 | HPGDS (0.33) | HPGDSSMYD3MGLL | |
| SCHEMBL13964566 | 0.73 | KMT2A (0.39) | MAPTRAB9ANPC1ALDH1A1KDM4E | |
| SCHEMBL1666784 | 0.67 | SMYD3 (0.46) | HPGDSSMYD3MAPTRAB9ANPC1 | |
| SCHEMBL1666783 | 0.67 | SMYD3 (0.46) | HPGDSSMYD3MAPTRAB9ABRD4 | |
| SCHEMBL1667322 | 0.67 | HPGDS (0.48) | HPGDSSMYD3MAPTRAB9ANPC1 | |
| SCHEMBL1667320 | 0.66 | HPGDS (0.49) | HPGDSSMYD3MAPTRAB9ANPC1 | |
| SCHEMBL1663882 | 0.65 | USP2 (0.55) | HPGDSMAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL1664403 | 0.65 | BRD4 (0.57) | HPGDSSMYD3RAB9ANPC1AR | |
| SCHEMBL1664406 | 0.65 | NPC1 (0.53) | HPGDSRAB9ANPC1BRD4MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103282034-A | Use of hematopoietic growth factor mimetics | LIGAND PHARM INC | 2013-09-04 | — | — | CN | disclosed |