Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 20/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL983143 | 0.90 | KCNN4 (0.48) | KCNN4 | |
| SCHEMBL985451 | 0.89 | KCNN4 (0.45) | KCNN4 | |
| SCHEMBL983000 | 0.89 | KCNN4 (0.52) | KCNN4 | |
| SCHEMBL986234 | 0.88 | KCNN4 (0.55) | KCNN4 | |
| SCHEMBL984978 | 0.88 | KCNN4 (0.50) | KCNN4 | |
| SCHEMBL985933 | 0.88 | FYN (0.53) | KCNN4 | |
| SCHEMBL985325 | 0.88 | KCNN4 (0.47) | KCNN4 | |
| SCHEMBL984379 | 0.88 | FYN (0.50) | KCNN4 | |
| SCHEMBL986496 | 0.86 | KCNN4 (0.48) | KCNN4 | |
| SCHEMBL986129 | 0.85 | ALDH1A1 (0.46) | KCNN4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101479255-B | C-MET protein kinase inhibitors for the treatment of proliferative disorders | VERTEX PHARMA | 2013-05-01 | — | — | CN | claimed |