SCHEMBL279197

SCHEMBL279197

COCc1ccc(N(c2ccc(COC)cc2)c2ccc(-c3ccccc3)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.50
AGXT P21549 2/20 0.50
TAAR1 Q96RJ0 2/20 0.46
GPR88 Q9GZN0 1/20 0.41
CHKA P35790 2/20 0.40
CNR2 P34972 1/20 0.39
GSTP1 P09211 1/20 0.39
PYCR1 P32322 1/20 0.38
FAAH O00519 1/20 0.38
MGLL Q99685 1/20 0.38
CARM1 Q86X55 1/20 0.38
PRMT1 Q99873 1/20 0.38
PTGES O14684 1/20 0.37
ALOX5 P09917 1/20 0.37
FFAR1 O14842 1/20 0.37
ABCC4 O15439 1/20 0.37
LMNA P02545 1/20 0.37
GAA P10253 1/20 0.37
TSHR P16473 1/20 0.37
PTGS1 P23219 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10330363 0.96 IDO1 (0.46) IDO1AGXTTAAR1GPR88CHKA
SCHEMBL14025867 0.95 IDO1 (0.46) IDO1AGXTTAAR1GPR88CHKA
SCHEMBL14025869 0.95 IDO1 (0.46) IDO1AGXTTAAR1GPR88CHKA
SCHEMBL308112 0.92 ERN1 (0.41) IDO1AGXTGPR88FAAHGAA
SCHEMBL279615 0.90 ALDH1A1 (0.45) IDO1AGXTGPR88CNR2FAAH
SCHEMBL279614 0.90 ALDH1A1 (0.45) IDO1AGXTGPR88CNR2FAAH
Biphenyl SCHEMBL27942111 0.88 IDO1 (0.61) IDO1AGXTTAAR1GSTP1FFAR1
SCHEMBL3146138 0.88 IDO1 (0.61) IDO1AGXTTAAR1GSTP1FFAR1
SCHEMBL279311 0.87 ERN1 (0.38) IDO1AGXTTAAR1GPR88GAA
SCHEMBL13681239 0.87 ERN1 (0.38) IDO1AGXTTAAR1GPR88GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9280073-B1 Image forming apparatus and process cartridge FUJI XEROX CO., LTD. (JP) 2016-03-08 US disclosed
US-9280073-B1 Image forming apparatus and process cartridge FUJI XEROX CO., LTD. (JP) 2016-03-08 US disclosed
US-9152120-B2 Cleaning blade, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2015-10-06 US disclosed
US-9152120-B2 Cleaning blade, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2015-10-06 US disclosed
US-8790854-B2 Electrophotographic photoreceptor, image forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2014-07-29 US disclosed
US-8790854-B2 Electrophotographic photoreceptor, image forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2014-07-29 US disclosed
US-20140086656-A1 CLEANING BLADE, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2014-03-27 US disclosed
US-20140086656-A1 CLEANING BLADE, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2014-03-27 US disclosed
US-8669028-B2 Electrophotographic photoreceptor, method for producing electrophotographic photoreceptor, image forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2014-03-11 US disclosed
US-8669028-B2 Electrophotographic photoreceptor, method for producing electrophotographic photoreceptor, image forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2014-03-11 US disclosed
US-20080089712-A1 Image forming apparatus and process cartridge FUJI XEROX CO., LTD. (JP) 2008-04-17 US disclosed
US-20080089712-A1 Image forming apparatus and process cartridge FUJI XEROX CO., LTD. (JP) 2008-04-17 US disclosed
US-20080031642-A1 Electrophotographic photoreceptor, image forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2008-02-07 US disclosed
US-20080031642-A1 Electrophotographic photoreceptor, image forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2008-02-07 US disclosed
US-20070231721-A1 Electrophotographic photoreceptor, process cartridge, image forming apparatus and coating composition FUJI XEROX CO., LTD. (JP) 2007-10-04 US disclosed
US-20070231721-A1 Electrophotographic photoreceptor, process cartridge, image forming apparatus and coating composition FUJI XEROX CO., LTD. (JP) 2007-10-04 US disclosed
US-20070148570-A1 Electrophotographic photoreceptor, process cartridge and image-forming apparatus FUJI XEROX CO., LTD. (JP) 2007-06-28 US disclosed
US-20070148570-A1 Electrophotographic photoreceptor, process cartridge and image-forming apparatus FUJI XEROX CO., LTD. (JP) 2007-06-28 US disclosed
US-20070003850-A1 Curable resin composition, electrophotographic photoreceptor, process cartridge, and image-forming apparatus FUJI XEROX CO., LTD. (JP) 2007-01-04 US disclosed
US-20070003850-A1 Curable resin composition, electrophotographic photoreceptor, process cartridge, and image-forming apparatus FUJI XEROX CO., LTD. (JP) 2007-01-04 US disclosed