1,4-Butanediol

1,4-Butanediol

SCHEMBL27920186

O=[PH](O)O.OCCCCO

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.41
GPR84 Q9NQS5 1/20 0.40
FFAR1 O14842 1/20 0.40
FFAR4 Q5NUL3 1/20 0.40
TSHR P16473 3/20 0.39
LMNA P02545 2/20 0.39
ALDH1A1 P00352 2/20 0.39
HSD17B10 Q99714 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
CAMK2A Q9UQM7 1/20 0.37
KDM4E B2RXH2 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1-Pentanol SCHEMBL10796803 0.84 SMN1; SMN2 (0.71) SMN1; SMN2TSHRLMNAALDH1A1HSD17B10
Phosphonic Acid SCHEMBL6897152 0.84 NFKB1 (0.41) GPR84FFAR1FFAR4TSHRLMNA
Phosphonic Acid SCHEMBL1682707 0.82
Phosphonic Acid SCHEMBL28321604 0.82 TSHR (0.50) TSHR
Phosphonic Acid SCHEMBL29098216 0.82 TSHR (0.50) TSHR
Decanol SCHEMBL25345185 0.82 TSHR (0.72) SMN1; SMN2GPR84TSHRLMNAALDH1A1
Dodecanol SCHEMBL5182014 0.82 TSHR (0.72) SMN1; SMN2GPR84TSHRLMNAALDH1A1
Cetyl Alcohol SCHEMBL5576621 0.82 TSHR (0.72) SMN1; SMN2GPR84TSHRLMNAALDH1A1
Undecanol SCHEMBL5576165 0.82 TSHR (0.72) SMN1; SMN2GPR84TSHRLMNAALDH1A1
Octanol SCHEMBL6433191 0.82 TSHR (0.72) SMN1; SMN2GPR84TSHRLMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103102490-A Phosphorus-containing polyol, preparation method thereof and flame-retardant polyurethane containing same BEIJING DECHEM CHEMICAL TECHNOLOGY CO LTD 2013-05-15 CN disclosed