SCHEMBL27920187

SCHEMBL27920187

CCc1c(C)nn(-c2ccccc2O)c1C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.46
CYP1A2 P05177 1/20 0.46
CYP2D6 P10635 1/20 0.46
HPGD P15428 1/20 0.46
HIF1A Q16665 1/20 0.46
HSD17B10 Q99714 1/20 0.46
NPC1 O15118 2/20 0.44
RAB9A P51151 2/20 0.44
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
PDE4B Q07343 1/20 0.41
TSHR P16473 2/20 0.39
LMNA P02545 2/20 0.38
ALOX15 P16050 1/20 0.38
KCNMA1 Q12791 1/20 0.38
CA12 O43570 2/20 0.38
CA1 P00915 2/20 0.38
CA2 P00918 2/20 0.38
CA9 Q16790 2/20 0.38
WNT3A P56704 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27920183 0.86 CA12 (0.52) ALDH1A1CYP1A2CYP2D6HPGDHIF1A
SCHEMBL17255699 0.80 HPGD (0.49) ALDH1A1CYP1A2CYP2D6HPGDHIF1A
SCHEMBL16857586 0.80 NPC1 (0.71) HSD17B10NPC1RAB9AMEN1KMT2A
SCHEMBL28102000 0.80 HSD17B10 (0.51) ALDH1A1CYP1A2CYP2D6HPGDHIF1A
SCHEMBL15442346 0.78 SMO (0.54) ALDH1A1MEN1KMT2APDE4BTSHR
SCHEMBL17255717 0.78 NPC1 (0.44) ALDH1A1CYP1A2CYP2D6HPGDHIF1A
SCHEMBL17255701 0.77 HPGD (0.49) ALDH1A1CYP1A2CYP2D6HPGDHIF1A
SCHEMBL16931730 0.77 TSHR (0.71) NPC1RAB9AMEN1KMT2APDE4B
SCHEMBL12770960 0.76 MEN1 (0.68) ALDH1A1HSD17B10NPC1RAB9AMEN1
SCHEMBL23402809 0.74 KMT2A (0.43) ALDH1A1NPC1RAB9AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103339112-B Topical antifungal agents MEIJI SEIKA PHARMA CO.,LTD. (JP) 2015-08-12 CN claimed
CN-103339112-A Topical antifungal agent MEIJI SEIKA PHARMA CO LTD 2013-10-02 CN claimed
CN-103339112-B Topical antifungal agents MEIJI SEIKA PHARMA CO.,LTD. (JP) 2015-08-12 CN disclosed
CN-104661661-A External liquid preparation for resisting trichophytosis MEIJI SEIKA PHARMA CO LTD 2015-05-27 CN disclosed
CN-103339112-A Topical antifungal agent MEIJI SEIKA PHARMA CO LTD 2013-10-02 CN disclosed