Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | CA9 | Q16790 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | XBP1 | P17861 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27920187 | 0.86 | ALDH1A1 (0.46) | CA12CA1CA2CA9NPC1 | |
| SCHEMBL16857586 | 0.82 | NPC1 (0.71) | CA12CA1CA2CA9NPC1 | |
| SCHEMBL16931730 | 0.79 | TSHR (0.71) | CA12CA1CA2CA9NPC1 | |
| SCHEMBL19675733 | 0.78 | NPC1 (0.66) | CA12CA1CA2CA9NPC1 | |
| SCHEMBL23401041 | 0.77 | POLB (0.40) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL17255699 | 0.76 | HPGD (0.49) | NPC1RAB9AALDH1A1LMNAHIF1A | |
| SCHEMBL28102000 | 0.76 | HSD17B10 (0.51) | CA12CA1CA2CA9NPC1 | |
| SCHEMBL16910807 | 0.74 | CA12 (0.44) | CA12CA1CA2CA9NPC1 | |
| SCHEMBL17255717 | 0.74 | NPC1 (0.44) | NPC1RAB9AALDH1A1HIF1AMAPT | |
| SCHEMBL17255701 | 0.73 | HPGD (0.49) | RAB9AALDH1A1HIF1AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103339112-B | Topical antifungal agents | MEIJI SEIKA PHARMA CO.,LTD. (JP) | 2015-08-12 | — | — | CN | claimed |
| CN-103339112-A | Topical antifungal agent | MEIJI SEIKA PHARMA CO LTD | 2013-10-02 | — | — | CN | claimed |
| CN-103339112-B | Topical antifungal agents | MEIJI SEIKA PHARMA CO.,LTD. (JP) | 2015-08-12 | — | — | CN | disclosed |
| CN-104661661-A | External liquid preparation for resisting trichophytosis | MEIJI SEIKA PHARMA CO LTD | 2015-05-27 | — | — | CN | disclosed |
| CN-103339112-A | Topical antifungal agent | MEIJI SEIKA PHARMA CO LTD | 2013-10-02 | — | — | CN | disclosed |