SCHEMBL27920541

SCHEMBL27920541

O=CC(=O)C1c2ccccc2CN1O

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ACE P12821 7/20 0.41
NOTUM Q6P988 1/20 0.34
LMNA P02545 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
HSP90AA1 P07900 7/20 0.34
HSP90AB1 P08238 7/20 0.34
MAPT P10636 2/20 0.33
KMT2A Q03164 2/20 0.33
ALDH1A1 P00352 1/20 0.33
HDAC4 P56524 1/20 0.33
HDAC7 Q8WUI4 1/20 0.33
HDAC5 Q9UQL6 1/20 0.33
MEN1 O00255 1/20 0.33
TAAR1 Q96RJ0 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Lactic Acid SCHEMBL28235195 0.89 ACE (0.43) ACEHSP90AA1HSP90AB1
SCHEMBL27982978 0.82 ACE (0.41) ACENOTUMLMNASMN1; SMN2HSP90AA1
SCHEMBL28361507 0.82 ACE (0.40) ACENOTUMLMNASMN1; SMN2HSP90AA1
SCHEMBL28234281 0.82 ACE (0.36) ACE
Benzene SCHEMBL28150775 0.80 ACE (0.42) ACELMNASMN1; SMN2HSP90AA1HSP90AB1
SCHEMBL28002392 0.80 ACE (0.42) ACELMNASMN1; SMN2HSP90AA1HSP90AB1
SCHEMBL27842630 0.80 ACE (0.39) ACELMNASMN1; SMN2HSP90AA1HSP90AB1
SCHEMBL27815974 0.78 ACE (0.40) ACENOTUMLMNASMN1; SMN2HSP90AA1
SCHEMBL27967789 0.78 ACE (0.41) ACEHSP90AA1HSP90AB1ALDH1A1
SCHEMBL28567508 0.77 ACE (0.37) ACELMNASMN1; SMN2HSP90AA1HSP90AB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111943939-B Synthesis method of chromanone compound and agricultural biological activity thereof 青岛农业大学 2022-05-24 CN claimed
CN-111943939-A Synthesis method of chromanone compound and agricultural biological activity thereof 青岛农业大学 2020-11-17 CN claimed
CN-113979981-B Sulfhydryl response type dealkalized site capture reagent and application 天津医科大学 2023-04-07 CN disclosed
CN-111943939-B Synthesis method of chromanone compound and agricultural biological activity thereof 青岛农业大学 2022-05-24 CN disclosed
CN-111943939-B Synthesis method of chromanone compound and agricultural biological activity thereof 青岛农业大学 2022-05-24 CN disclosed
CN-113979981-A Sulfhydryl response type dealkalized site capture reagent and application 天津医科大学 2022-01-28 CN disclosed
CN-111943939-A Synthesis method of chromanone compound and agricultural biological activity thereof 青岛农业大学 2020-11-17 CN disclosed
CN-111943939-A Synthesis method of chromanone compound and agricultural biological activity thereof 青岛农业大学 2020-11-17 CN disclosed
CN-109302846-A Indolinone compounds and their use in the treatment of fibrotic diseases 莱斯彼维特有限公司 2019-02-01 CN disclosed
CN-105025715-B Pesticidal compositions and methods related thereto 美国陶氏益农公司 2018-11-16 CN disclosed
CN-108778273-A bicyclic aryl monocyclic β -lactam compounds and methods of use thereof for treating bacterial infections 默沙东公司 2018-11-09 CN disclosed
CN-102781909-B N-alkoxyamide conjugates as imaging agents LANTHEUS MEDICAL IMAGING INC 2015-06-17 CN disclosed
CN-104619707-A Condensed ring heterocyclic compound KYOWA HAKKO KIRIN CO LTD 2015-05-13 CN disclosed
CN-103965128-A N-alkoxyamide Conjugates As Imaging Agents LANTHEUS MEDICAL IMAGING INC 2014-08-06 CN disclosed
CN-101970015-B N-alkoxyamide conjugates as imaging agents LANTHEUS MEDICAL IMAGING INC 2014-05-07 CN disclosed
CN-103492384-A Compounds and compositions as trk inhibitors IRM LLC 2014-01-01 CN disclosed
CN-101983191-B Oxim derivatives as hsp90 inhibitors TAKEDA PHARMACEUTICAL 2013-11-20 CN disclosed
CN-103096933-A Multifunctional antibody conjugates COVX TECHNOLOGIES IRELAND LTD 2013-05-08 CN disclosed
CN-102781909-A N-alkoxyamide conjugates as imaging agents LANTHEUS MEDICAL IMAGING INC 2012-11-14 CN disclosed
CN-101983191-A Oxim derivatives as hsp90 inhibitors TAKEDA PHARMACEUTICAL 2011-03-02 CN disclosed