Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 8/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28002392 | 1.00 | ACE (0.42) | ACECYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL28056681 | 0.89 | SLC6A2 (0.38) | ACESLC6A2SLC6A4SLC6A3HSP90AA1 | |
| SCHEMBL28131035 | 0.88 | FFAR1 (0.45) | ACESMN1; SMN2HTT | |
| SCHEMBL28002394 | 0.88 | ACE (0.36) | ACECYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL28041236 | 0.81 | ACE (0.36) | ACEHSP90AA1HSP90AB1 | |
| SCHEMBL28234415 | 0.81 | ACE (0.36) | ACECYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL27846951 | 0.80 | SLC6A2 (0.37) | ACESLC6A2SLC6A4SLC6A3SMN1; SMN2 | |
| SCHEMBL28281951 | 0.80 | ACE (0.36) | ACELMNASMN1; SMN2HTT | |
| SCHEMBL27920541 | 0.80 | ACE (0.41) | ACEHSP90AA1HSP90AB1LMNASMN1; SMN2 | |
| SCHEMBL28361507 | 0.78 | ACE (0.40) | ACEHSP90AA1HSP90AB1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106661205-A | Particulate amine-functionalized polyaryletherketone polymers and copolymers thereof | 塞特工业公司 | 2017-05-10 | — | — | CN | disclosed |