Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 2/20 | 0.44 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.44 |
| ▸ | PNP | P00491 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24879211 | 0.85 | GAA (0.50) | GAAPKMTSHRKMT2AKDM4E | |
| SCHEMBL8771674 | 0.83 | GAA (0.58) | GAAPKMTSHRKMT2AKDM4E | |
| SCHEMBL5738369 | 0.77 | CACNA1H (0.36) | GAATDP1 | |
| SCHEMBL6759193 | 0.76 | GAA (0.54) | GAAPKMTSHRKMT2AKDM4E | |
| SCHEMBL27816872 | 0.75 | GAA (0.53) | GAAPKMTSHRKMT2AKDM4E | |
| SCHEMBL28217562 | 0.74 | GAA (0.60) | GAAPKMTSHRKMT2AKDM4E | |
| SCHEMBL6542837 | 0.74 | GAA (0.60) | GAAPKMTSHRKMT2AKDM4E | |
| SCHEMBL27456762 | 0.74 | GAA (0.51) | GAAPKMTSHRKMT2AKDM4E | |
| SCHEMBL28839113 | 0.73 | GAA (0.58) | GAAPKMTSHRKMT2AKDM4E | |
| SCHEMBL9540475 | 0.73 | GAA (0.58) | GAAPKMTSHRKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103058931-B | Four 2-(3', 5'-dihalo-benzyl) benzimidazole type novel compounds and preparation method thereof | GUANGDONG TONESET SCIENCE & TECHNOLOGY CO LTD | 2015-07-01 | — | — | CN | disclosed |
| CN-103058931-A | Four 2-(3', 5'-dihalo-benzyl) benzimidazole type novel compounds and preparation method thereof | GUANGDONG TONESET SCIENCE & TECHNOLOGY CO LTD | 2013-04-24 | — | — | CN | disclosed |