Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 16/20 | 0.67 |
| ▸ | HASPIN | Q8TF76 | 4/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8852076 | 0.87 | DYRK1A (0.70) | DYRK1AHASPIN | |
| SCHEMBL27939720 | 0.85 | DYRK1A (0.50) | DYRK1AHASPINACHEMAOAHTR2A | |
| SCHEMBL29061172 | 0.84 | DYRK1A (0.49) | DYRK1AHASPINACHEMAOAHTR2A | |
| SCHEMBL16123659 | 0.83 | DYRK1A (0.71) | DYRK1AHASPINHTR2AHTR2C | |
| SCHEMBL12070353 | 0.83 | DYRK1A (0.73) | DYRK1AHASPINACHEMAOAHTR2A | |
| SCHEMBL30939988 | 0.83 | DYRK1A (0.71) | DYRK1AHASPINHTR2AHTR2C | |
| SCHEMBL19946130 | 0.82 | AAK1 (0.55) | DYRK1A | |
| SCHEMBL12288128 | 0.82 | HASPIN (0.74) | DYRK1AHASPIN | |
| SCHEMBL30939875 | 0.82 | HASPIN (0.74) | DYRK1AHASPIN | |
| SCHEMBL16123596 | 0.81 | DYRK1A (0.55) | DYRK1AHASPINHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115417887-A | 9-alkyl di-dehydro harmine derivative and preparation method and application thereof | 延安大学 | 2022-12-02 | — | — | CN | claimed |
| CN-115417887-B | 9-alkyl double-dehydro harmine derivative and preparation method and application thereof | 延安大学 | 2024-02-13 | — | — | CN | disclosed |
| CN-115417887-A | 9-alkyl di-dehydro harmine derivative and preparation method and application thereof | 延安大学 | 2022-12-02 | — | — | CN | disclosed |
| CN-101429198-B | Banisterine derivant and uses thereof | XINJIANG HUASHIDAN MEDICAMENTS RES CO LTD | 2013-10-23 | — | — | CN | disclosed |