Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 14/20 | 0.70 |
| ▸ | HASPIN | Q8TF76 | 7/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12288128 | 0.88 | HASPIN (0.74) | DYRK1AHASPIN | |
| SCHEMBL30939875 | 0.88 | HASPIN (0.74) | DYRK1AHASPIN | |
| SCHEMBL30939902 | 0.87 | DYRK1A (0.55) | DYRK1AHASPIN | |
| SCHEMBL16123596 | 0.87 | DYRK1A (0.55) | DYRK1AHASPIN | |
| SCHEMBL27921175 | 0.87 | DYRK1A (0.67) | DYRK1AHASPIN | |
| SCHEMBL27899833 | 0.84 | DYRK1A (0.55) | DYRK1AHASPIN | |
| SCHEMBL30939988 | 0.84 | DYRK1A (0.71) | DYRK1AHASPIN | |
| SCHEMBL16123659 | 0.84 | DYRK1A (0.71) | DYRK1AHASPIN | |
| SCHEMBL17102959 | 0.84 | DYRK1A (0.84) | DYRK1AHASPIN | |
| SCHEMBL2217125 | 0.82 | DYRK1A (1.00) | DYRK1AHASPIN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101429198-B | Banisterine derivant and uses thereof | XINJIANG HUASHIDAN MEDICAMENTS RES CO LTD | 2013-10-23 | — | — | CN | disclosed |
| CN-103070862-A | Application of harmine derivative in preparation of antibacterial drugs | XINJIANG HUASHIDAN PHARMACEUTICAL RES CO LTD | 2013-05-01 | — | — | CN | disclosed |
| US-5591738-A | Method of treating chemical dependency using β-carboline alkaloids, derivatives and salts thereof | NDA INTERNATIONAL, INC. (US) | 1997-01-07 | — | — | US | disclosed |