Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 2/20 | 0.67 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9415751 | 0.86 | GLA (0.67) | GLARAB9AL3MBTL1POLBLMNA | |
| SCHEMBL19574225 | 0.84 | ATM (0.75) | GLARAB9AL3MBTL1POLBLMNA | |
| SCHEMBL7694058 | 0.84 | GLA (0.65) | GLARAB9AL3MBTL1POLBLMNA | |
| SCHEMBL19574088 | 0.82 | ATM (0.72) | GLARAB9AL3MBTL1POLBLMNA | |
| SCHEMBL20520314 | 0.82 | GLA (0.64) | GLARAB9AL3MBTL1POLBLMNA | |
| SCHEMBL253804 | 0.82 | GLA (0.64) | GLARAB9AL3MBTL1POLBLMNA | |
| SCHEMBL2947983 | 0.82 | GLA (0.64) | GLARAB9AL3MBTL1POLBLMNA | |
| SCHEMBL20780402 | 0.81 | GLA (0.63) | GLARAB9AL3MBTL1POLBLMNA | |
| SCHEMBL4245553 | 0.81 | GLA (0.62) | GLARAB9AL3MBTL1POLBLMNA | |
| SCHEMBL2718359 | 0.81 | L3MBTL1 (0.69) | GLARAB9AL3MBTL1POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103068824-A | Novel 3, 5-disubstituted-3H-imidazo [4,5-B ] pyridines and 3, 5-disubstituted-3H- [1,2,3] triazolo [4,5-B ] pyridine compounds as protein kinase modulators | INDIAN INCOZEN THERAPEUTICS PVT LTD | 2013-04-24 | — | — | CN | disclosed |