Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 13/20 | 0.64 |
| ▸ | AXL | P30530 | 1/20 | 0.64 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.64 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.64 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL207818 | 0.89 | CYP19A1 (0.64) | CYP19A1AXLPBRM1MKNK1MKNK2 | |
| SCHEMBL717060 | 0.87 | CYP19A1 (0.66) | CYP19A1AXLPBRM1MKNK1MKNK2 | |
| SCHEMBL17014792 | 0.85 | CYP19A1 (0.70) | CYP19A1AXLPBRM1MKNK1MKNK2 | |
| SCHEMBL719078 | 0.84 | CYP19A1 (0.61) | CYP19A1AXLPBRM1MKNK1MKNK2 | |
| SCHEMBL6798787 | 0.81 | CYP19A1 (0.72) | CYP19A1AXLPBRM1MKNK1MKNK2 | |
| SCHEMBL14320817 | 0.80 | RAB9A (0.77) | CYP19A1AXLPBRM1MKNK1MKNK2 | |
| SCHEMBL6196239 | 0.79 | CYP19A1 (1.00) | CYP19A1AXLPBRM1MKNK1MKNK2 | |
| SCHEMBL19051411 | 0.76 | CYP19A1 (1.00) | CYP19A1AXLPBRM1MKNK1MKNK2 | |
| SCHEMBL17014786 | 0.76 | CYP19A1 (1.00) | CYP19A1AXLPBRM1MKNK1MKNK2 | |
| SCHEMBL30128572 | 0.76 | CYP19A1 (1.00) | CYP19A1AXLPBRM1MKNK1MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103130791-A | Novel benzamides compound | JIANGSU CHIA TAI TIANQING PHAR | 2013-06-05 | — | — | CN | disclosed |