Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KB2 | Q9UBS0 | 1/20 | 0.46 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.45 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.45 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | CCNC | P24863 | 2/20 | 0.41 |
| ▸ | CDK8 | P49336 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | PTGFR | P43088 | 1/20 | 0.40 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.40 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.40 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27905840 | 0.86 | CDC7 (0.42) | FTOCCNCCDK8PDE10A | |
| SCHEMBL624538 | 0.72 | CDC7 (0.46) | FTOCCNCCDK8TBXA2RPTGER4 | |
| SCHEMBL1725901 | 0.70 | KDM4C (0.59) | MKNK1MKNK2HPGDKDM4E | |
| SCHEMBL1724770 | 0.69 | MKNK1 (0.56) | RPS6KB2MKNK1MKNK2HPGDKDM4E | |
| SCHEMBL23110040 | 0.68 | MEN1 (0.67) | RPS6KB2MKNK1MKNK2HPGDKDM4E | |
| SCHEMBL1724808 | 0.68 | KDM4C (0.53) | MKNK1MKNK2HPGDKDM4EALDH1A1 | |
| SCHEMBL3591688 | 0.66 | MKNK1 (0.41) | MKNK1MKNK2HPGDALDH1A1TDP1 | |
| SCHEMBL12076008 | 0.66 | HPGD (0.62) | MKNK1MKNK2HPGDKDM4EALDH1A1 | |
| SCHEMBL16670764 | 0.65 | TSHR (0.63) | FTOTBXA2RPTGER4PTGFRPTGER3 | |
| SCHEMBL24573252 | 0.65 | HPGD (0.66) | RPS6KB2HPGDKDM4EALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103153300-A | Heteroaryls and uses thereof | MILLENNIUM PHARM INC | 2013-06-12 | — | — | CN | disclosed |