Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.37 |
| ▸ | PNMT | P11086 | 3/20 | 0.35 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.32 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | AOC3 | Q16853 | 5/20 | 0.32 |
| ▸ | AOC1 | P19801 | 4/20 | 0.32 |
| ▸ | NCF1 | P14598 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1315359 | 0.80 | ROCK2 (0.35) | — | |
| SCHEMBL16694657 | 0.80 | KMT2A (0.39) | CYP2D6 | |
| SCHEMBL1314189 | 0.78 | ROCK2 (0.33) | — | |
| SCHEMBL17583591 | 0.77 | ROCK2 (0.33) | — | |
| SCHEMBL28859669 | 0.76 | KMT2A (0.31) | — | |
| SCHEMBL14905782 | 0.76 | GAA (0.43) | CYP3A4 | |
| SCHEMBL520084 | 0.75 | BCHE (0.37) | — | |
| SCHEMBL2846316 | 0.75 | TAAR1 (0.34) | CYP3A4CYP2D6 | |
| SCHEMBL16695057 | 0.75 | KMT2A (0.35) | — | |
| Formaldehyde SCHEMBL17583570 | 0.73 | ROCK2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103384665-B | The method for preparing gyrase and topoisomerase enzyme inhibitor | 斯派罗吹耐姆公司 | 2018-01-09 | — | — | CN | disclosed |
| CN-103384665-A | Process of making gyrase and topoisomerase IV inhibitors | VERTEX PHARMA | 2013-11-06 | — | — | CN | disclosed |