Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 5/20 | 0.54 |
| ▸ | RAB9A | P51151 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | CASP3 | P42574 | 2/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30620627 | 0.90 | NPC1 (0.60) | L3MBTL1NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL27817990 | 0.90 | NPC1 (0.60) | L3MBTL1NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL8069269 | 0.84 | NPC1 (0.51) | NPC1RAB9ASMN1; SMN2LMNAKMT2A | |
| SCHEMBL11527522 | 0.84 | NPC1 (0.64) | L3MBTL1NPC1RAB9ASMN1; SMN2LMNA | |
| Iodomethane SCHEMBL11478139 | 0.81 | RAB9A (0.57) | L3MBTL1NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL20918141 | 0.80 | NPSR1 (0.58) | L3MBTL1NPC1RAB9ASMN1; SMN2LMNA | |
| Iodomethane SCHEMBL11489847 | 0.80 | KMT2A (0.59) | NPC1RAB9ASMN1; SMN2KMT2APARP10 | |
| SCHEMBL11529772 | 0.80 | KMT2A (0.58) | L3MBTL1NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL20509994 | 0.79 | SMN1; SMN2 (0.63) | NPC1RAB9ASMN1; SMN2LMNAKDM4E | |
| SCHEMBL4014798 | 0.79 | TDP1 (0.54) | L3MBTL1RAB9ASMN1; SMN2LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105685064-A | HERBICIDAL ISOXAZOLO[5,4-b]PYRIDINES | 巴斯夫欧洲公司 | 2016-06-22 | — | — | CN | claimed |
| CN-103124733-B | Herbicidal isoxazolo [5,4-b ] pyridines | BASF SE (DE) | 2016-03-30 | — | — | CN | claimed |
| CN-103124733-A | Herbicidal isoxazolo [5,4-b ] pyridines | BASF SE | 2013-05-29 | — | — | CN | claimed |
| CN-105685064-B | Weeding isoxazoles simultaneously [5,4-b] pyridine | 巴斯夫欧洲公司 | 2018-06-22 | — | — | CN | disclosed |
| CN-105685064-A | HERBICIDAL ISOXAZOLO[5,4-b]PYRIDINES | 巴斯夫欧洲公司 | 2016-06-22 | — | — | CN | disclosed |
| CN-103124733-B | Herbicidal isoxazolo [5,4-b ] pyridines | BASF SE (DE) | 2016-03-30 | — | — | CN | disclosed |
| CN-103124733-A | Herbicidal isoxazolo [5,4-b ] pyridines | BASF SE | 2013-05-29 | — | — | CN | disclosed |