SCHEMBL27925973

SCHEMBL27925973

O=C(O)C1CC(F)CN1F

nearest known ligand 0.38

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28311654 0.77 ATM (0.53) ATM
SCHEMBL19974510 0.77 ATM (0.53) ATM
SCHEMBL13101906 0.77 ATM (0.53) ATM
SCHEMBL30438193 0.77 ATM (0.53) ATM
SCHEMBL5068781 0.76 ATM (0.42) ATM
SCHEMBL22029235 0.76 ATM (0.42) ATM
SCHEMBL16105109 0.76 ATM (0.42) ATM
SCHEMBL22360773 0.76 ATM (0.38) ATM
SCHEMBL17995266 0.76 ATM (0.38) ATM
SCHEMBL19540491 0.76 ATM (0.38) ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103429607-B There is the triterpenoid that C-17 and C-3 of HIV maturation inhibit activities is modified BRISTOL-MYERS SQUIBB CO. (US) 2016-02-17 CN disclosed
CN-103429607-A C-17 and C-3 modified triterpenoids with HIV maturation inhibitory activity BRISTOL MYERS SQUIBB CO 2013-12-04 CN disclosed