SCHEMBL279262

SCHEMBL279262

O=C(O)CCc1ccc(N(c2ccccc2)c2ccc(-c3ccc(N(c4ccccc4)c4ccc(CCC(=O)O)cc4)cc3)cc2)cc1

nearest known ligand 0.73

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 15/20 0.73
KEAP1 Q14145 1/20 0.60
FFAR4 Q5NUL3 7/20 0.56
MMP12 P39900 1/20 0.56
PTGES O14684 1/20 0.50
ALOX5 P09917 1/20 0.50
RXRA P19793 1/20 0.50
RXRB P28702 1/20 0.50
RXRG P48443 1/20 0.50
AKR1B1 P15121 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17321106 1.00 FFAR1 (0.73) FFAR1KEAP1FFAR4MMP12PTGES
SCHEMBL279537 0.97 FFAR1 (0.79) FFAR1KEAP1FFAR4MMP12PTGES
SCHEMBL14732635 0.95 FFAR1 (0.77) FFAR1KEAP1FFAR4MMP12PTGES
SCHEMBL11437198 0.95 FFAR1 (0.68) FFAR1KEAP1FFAR4
SCHEMBL25933402 0.95 FFAR1 (0.68) FFAR1KEAP1FFAR4
SCHEMBL9607494 0.94 FFAR1 (0.65) FFAR1KEAP1FFAR4MMP12PTGES
SCHEMBL14732629 0.93 FFAR1 (0.71) FFAR1KEAP1FFAR4
SCHEMBL25976716 0.91 FFAR1 (0.70) FFAR1KEAP1FFAR4MMP12PTGES
SCHEMBL17321096 0.88 FFAR1 (0.61) FFAR1KEAP1FFAR4MMP12RXRA
SCHEMBL14732640 0.87 FFAR1 (0.67) FFAR1KEAP1FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8426093-B2 photosensitive layer has a charge transferring compound having hole transportation ability; hardening by heating, stable electrical properties FUJI XEROX CO., LTD. (JP) 2013-04-23 US disclosed
US-8426093-B2 photosensitive layer has a charge transferring compound having hole transportation ability; hardening by heating, stable electrical properties FUJI XEROX CO., LTD. (JP) 2013-04-23 US disclosed
US-8273517-B2 Method of manufacturing electrophotographic photoreceptor, electrophotographic photoreceptor, image-forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2012-09-25 US disclosed
US-8263299-B2 Multilayer; electroconductive support, photosensitive layer of cured phenolic resin having dynamics hardness and elastic deformation; xerography;thin film with few defects;mechanical strength; stability; high quality images FUJI XEROX CO., LTD. (JP) 2012-09-11 US disclosed
US-8263299-B2 Multilayer; electroconductive support, photosensitive layer of cured phenolic resin having dynamics hardness and elastic deformation; xerography;thin film with few defects;mechanical strength; stability; high quality images FUJI XEROX CO., LTD. (JP) 2012-09-11 US disclosed
US-20120134713-A1 METHOD OF MANUFACTURING ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE-FORMING APPARATUS, AND PROCESS CARTRIDGE FUJI XEROX CO., LTD. (JP) 2012-05-31 US disclosed
US-8133645-B2 Method of manufacturing electrophotographic photoreceptor, electrophotographic photoreceptor, image-forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2012-03-13 US disclosed
US-8055153-B2 Image forming apparatus and process cartridge FUJI XEROX CO., LTD. (JP) 2011-11-08 US disclosed
US-8055153-B2 Image forming apparatus and process cartridge FUJI XEROX CO., LTD. (JP) 2011-11-08 US disclosed
US-7951516-B2 photographic and electrophotographic apparatus having cylindrical supports, charge generating and charge transporting layers and protective coatings comprising curable resins and thermoplastic resins; durability FUJI XEROX CO., LTD. (JP) 2011-05-31 US disclosed
US-20070231721-A1 Electrophotographic photoreceptor, process cartridge, image forming apparatus and coating composition FUJI XEROX CO., LTD. (JP) 2007-10-04 US disclosed
US-20070231721-A1 Electrophotographic photoreceptor, process cartridge, image forming apparatus and coating composition FUJI XEROX CO., LTD. (JP) 2007-10-04 US disclosed
US-20070201917-A1 Image forming method and image forming apparatus FUJI XEROX CO., LTD. 2007-08-30 US disclosed
US-20070201917-A1 Image forming method and image forming apparatus FUJI XEROX CO., LTD. 2007-08-30 US disclosed
US-20070092821-A1 Toner for electrostatic image development, electrostatic image developer and image forming method using the same FUJI XEROX CO., LTD. (JP) 2007-04-26 US disclosed
US-20070092821-A1 Toner for electrostatic image development, electrostatic image developer and image forming method using the same FUJI XEROX CO., LTD. (JP) 2007-04-26 US disclosed
US-20070065741-A1 Electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2007-03-22 US disclosed
US-20070065741-A1 Electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2007-03-22 US disclosed
US-20070003850-A1 Curable resin composition, electrophotographic photoreceptor, process cartridge, and image-forming apparatus FUJI XEROX CO., LTD. (JP) 2007-01-04 US disclosed
US-20070003850-A1 Curable resin composition, electrophotographic photoreceptor, process cartridge, and image-forming apparatus FUJI XEROX CO., LTD. (JP) 2007-01-04 US disclosed