SCHEMBL279537

SCHEMBL279537

O=C(O)CCc1ccc(N(c2ccc(CCC(=O)O)cc2)c2ccc(-c3ccccc3)cc2)cc1

nearest known ligand 0.79

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 12/20 0.79
FFAR4 Q5NUL3 4/20 0.60
MMP12 P39900 2/20 0.60
KEAP1 Q14145 1/20 0.60
PTGES O14684 1/20 0.53
ALOX5 P09917 1/20 0.53
ABCC4 O15439 1/20 0.52
LMNA P02545 1/20 0.52
GAA P10253 1/20 0.52
TSHR P16473 1/20 0.52
PTGS1 P23219 1/20 0.52
HTT P42858 1/20 0.52
AKR1B1 P15121 1/20 0.51
NAAA Q02083 1/20 0.50
RXRA P19793 1/20 0.50
RXRB P28702 1/20 0.50
RXRG P48443 1/20 0.50
MMP13 P45452 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14732635 0.98 FFAR1 (0.77) FFAR1FFAR4MMP12KEAP1PTGES
SCHEMBL279262 0.97 FFAR1 (0.73) FFAR1FFAR4MMP12KEAP1PTGES
SCHEMBL17321106 0.97 FFAR1 (0.73) FFAR1FFAR4MMP12KEAP1PTGES
SCHEMBL25976716 0.94 FFAR1 (0.70) FFAR1FFAR4MMP12KEAP1PTGES
SCHEMBL11437198 0.91 FFAR1 (0.68) FFAR1FFAR4KEAP1
SCHEMBL25933402 0.91 FFAR1 (0.68) FFAR1FFAR4KEAP1
SCHEMBL9607494 0.91 FFAR1 (0.65) FFAR1FFAR4MMP12KEAP1PTGES
SCHEMBL15277868 0.90 FFAR1 (0.64) FFAR1FFAR4MMP12ABCC4LMNA
SCHEMBL14732629 0.89 FFAR1 (0.71) FFAR1FFAR4KEAP1
SCHEMBL1211561 0.89 FFAR1 (1.00) FFAR1FFAR4MMP12KEAP1ABCC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 160 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230259047-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, ELECTROPHOTOGRAPHIC APPARATUS, AND METHOD OF PRODUCING ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER CANON KABUSHIKI KAISHA (JP) 2023-08-17 US disclosed
US-20230259047-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, ELECTROPHOTOGRAPHIC APPARATUS, AND METHOD OF PRODUCING ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER CANON KABUSHIKI KAISHA (JP) 2023-08-17 US disclosed
US-20230259048-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, ELECTROPHOTOGRAPHIC APPARATUS, PROCESS CARTRIDGE, AND METHOD FOR PRODUCING ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER CANON KABUSHIKI KAISHA (JP) 2023-08-17 US disclosed
US-20230259048-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, ELECTROPHOTOGRAPHIC APPARATUS, PROCESS CARTRIDGE, AND METHOD FOR PRODUCING ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER CANON KABUSHIKI KAISHA (JP) 2023-08-17 US disclosed
US-10935898-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2021-03-02 US disclosed
US-20200124996-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2020-04-23 US disclosed
US-9280073-B1 Image forming apparatus and process cartridge FUJI XEROX CO., LTD. (JP) 2016-03-08 US disclosed
US-9280073-B1 Image forming apparatus and process cartridge FUJI XEROX CO., LTD. (JP) 2016-03-08 US disclosed
US-9188885-B2 Reactive compound, charge transporting film, photoelectric conversion device, electrophotographic photoreceptor and method of producing the same, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2015-11-17 US disclosed
US-9188885-B2 Reactive compound, charge transporting film, photoelectric conversion device, electrophotographic photoreceptor and method of producing the same, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2015-11-17 US disclosed
US-20070231721-A1 Electrophotographic photoreceptor, process cartridge, image forming apparatus and coating composition FUJI XEROX CO., LTD. (JP) 2007-10-04 US disclosed
US-20070231721-A1 Electrophotographic photoreceptor, process cartridge, image forming apparatus and coating composition FUJI XEROX CO., LTD. (JP) 2007-10-04 US disclosed
US-20070201917-A1 Image forming method and image forming apparatus FUJI XEROX CO., LTD. 2007-08-30 US disclosed
US-20070201917-A1 Image forming method and image forming apparatus FUJI XEROX CO., LTD. 2007-08-30 US disclosed
US-7262314-B2 3-iodopropylmethyldiisopropoxysilane and imaging members including the same XEROX CORPORATION (US) 2007-08-28 US disclosed
US-7262314-B2 3-iodopropylmethyldiisopropoxysilane and imaging members including the same XEROX CORPORATION (US) 2007-08-28 US disclosed
US-20070065741-A1 Electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2007-03-22 US disclosed
US-20070065741-A1 Electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2007-03-22 US disclosed
US-20070003850-A1 Curable resin composition, electrophotographic photoreceptor, process cartridge, and image-forming apparatus FUJI XEROX CO., LTD. (JP) 2007-01-04 US disclosed
US-20070003850-A1 Curable resin composition, electrophotographic photoreceptor, process cartridge, and image-forming apparatus FUJI XEROX CO., LTD. (JP) 2007-01-04 US disclosed